Results 131 to 140 of about 193,013 (355)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

open access: yesInterdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu   +6 more
wiley   +1 more source

Association between diabetic nephropathy and other diabetic microvascular and macrovascular complications

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2008
Diabetic nephropathy is found to be significantly associated with diabetic retino-pathy and coronary artery disease. Few studies have also shown an association between diabetic nephropathy and neuropathy, and peripheral vascular disease.
Chandy Anila   +3 more
doaj  

The association between testosterone levels and diabetic nephropathy in Egyptian men with type 1 Diabetes Mellitus

open access: yesEndocrine and Metabolic Science
Background: Type 1 diabetes mellitus is a chronic illness characterized by the body's inability to produce insulin due to the autoimmune destruction of beta cells in the pancreas. It can develop in adults and is often onset in childhood.
Mina Michael Nesim   +4 more
doaj   +1 more source

DIABETIC NEPHROPATHY [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 1955
openaire   +2 more sources

Glycemic Regulation and Renal Function by Heavy Metal Exposure: A Cross‐Sectional Analysis on Cement Plant Workers

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Heavy metal exposure is known to have various effects on renal function and blood glucose regulation. The main objective of this study was to evaluate the effects of cement dust and some metal (cadmium, manganese, nickel, and zinc) exposure on blood glucose and renal function parameters in male cement plant workers.
Duygu Seyhan Erdoğan   +5 more
wiley   +1 more source

Diabetic nephropathy [PDF]

open access: yesClinical Medicine, 2012
Wylie, Emma C, Satchell, Simon C
openaire   +2 more sources

Immune Imbalance in Sickle Cell Anemia: Flow Cytometric Insights Into Regulatory T Cells and Neutrophil Dynamics

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Flow cytometric analysis in sickle cell anemia reveals preserved Treg frequency despite decreased CD25 expression and increased neutrophil activity, highlighting a complex immune imbalance. The proportions of both neutrophil and lymphocyte cells have been shown to be a reliable predictor of CD3+ T cell levels, thus emphasizing the importance of innate ...
Rukiye Ölçüoğlu   +7 more
wiley   +1 more source

Incidence and Predictors of Diabetic Nephropathy among Type 2 Diabetes Mellitus Patients, Southern Ethiopia

open access: yesJournal of Nutrition and Metabolism
Background. Diabetic nephropathy is the most common cause of end-stage renal disease, and it brings high morbidity and mortality. Globally, the predominant rise in type II diabetes prevalence significantly increases the incidence of diabetic nephropathy.
Fasika Merid   +3 more
doaj   +1 more source

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