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Medicine, 2002
Diabetic nephropathy is diagnosed by the appearance of microalbuminuria and progresses to macroalbuminuria and end-stage kidney disease. Thus, it is important to estimate the urinary albumin excretion and glomerular filtration rates. The main targets of the treatment of diabetic nephropathy include hyperglycemia and glomerular hypertension. The results
Stephen Thomas, GianCarlo Viberti
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Diabetic nephropathy is diagnosed by the appearance of microalbuminuria and progresses to macroalbuminuria and end-stage kidney disease. Thus, it is important to estimate the urinary albumin excretion and glomerular filtration rates. The main targets of the treatment of diabetic nephropathy include hyperglycemia and glomerular hypertension. The results
Stephen Thomas, GianCarlo Viberti
openaire +5 more sources
Current Opinion in Internal Medicine, 2003
Diabetic nephropathy is the single most common disorder leading to renal failure. Its annual incidence has more than doubled in the past decade to reach 44% of all end-stage renal disease, despite recent therapeutic advances. Thus, research into diabetic nephropathy pathophysiology that could lead to new treatment approaches is urgently needed and this
Michael Mauer, Luiza M. Caramori
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Diabetic nephropathy is the single most common disorder leading to renal failure. Its annual incidence has more than doubled in the past decade to reach 44% of all end-stage renal disease, despite recent therapeutic advances. Thus, research into diabetic nephropathy pathophysiology that could lead to new treatment approaches is urgently needed and this
Michael Mauer, Luiza M. Caramori
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Current therapy in endocrinology and metabolism, 1997
Diabetic nephropathy accounts for almost a third of all causes of ESRD. Microalbuminuria screening among diabetics can offer early detection of incipient nephropathy. Aggressive treatment with ACE inhibitors may delay the onset of overt renal failure or delay its progression.
CASTELLINO, Pietro +2 more
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Diabetic nephropathy accounts for almost a third of all causes of ESRD. Microalbuminuria screening among diabetics can offer early detection of incipient nephropathy. Aggressive treatment with ACE inhibitors may delay the onset of overt renal failure or delay its progression.
CASTELLINO, Pietro +2 more
openaire +6 more sources
Clinical Cornerstone, 2003
As the epidemic of diabetes spreads so does the number of patients at risk for developing diabetic nephropathy, which occurs in 20% to 40% of all diabetic patients. Indeed, diabetes is the most common cause of end-stage renal disease (ESRD) in the United States, accounting for > 40% of patients starting renal replacement therapy each year ...
Mark E, Molitch +5 more
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As the epidemic of diabetes spreads so does the number of patients at risk for developing diabetic nephropathy, which occurs in 20% to 40% of all diabetic patients. Indeed, diabetes is the most common cause of end-stage renal disease (ESRD) in the United States, accounting for > 40% of patients starting renal replacement therapy each year ...
Mark E, Molitch +5 more
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Diabetic Nephropathy and Pregnancy
Clinical Obstetrics and Gynecology, 1991Knowledge of the pathogenic mechanisms of diabetic nephropathy (by which hyperglycemia, hyperfiltration, and hypertension cause the gradual development of microproteinuria, mesangial expansion, and eventual glomerular closure) provides the basis for effective treatment.
C. Andrew Combs, John L. Kitzmiller
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Diabetes Technology & Therapeutics, 1999
Renal involvement is one of the major microvascular complications of both type 1 and type 2 diabetes mellitus. Diabetic nephropathy is the major cause of end-stage renal failure in most Western nations and is associated with increased morbidity and mortality as compared to other causes of renal disease. The pathogenesis of renal involvement in diabetes
G, Boner, M E, Cooper
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Renal involvement is one of the major microvascular complications of both type 1 and type 2 diabetes mellitus. Diabetic nephropathy is the major cause of end-stage renal failure in most Western nations and is associated with increased morbidity and mortality as compared to other causes of renal disease. The pathogenesis of renal involvement in diabetes
G, Boner, M E, Cooper
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Disease-a-Month, 1993
Diabetic nephropathy occurs in approximately 35% of all diabetic patients, both insulin and non-insulin dependent. It accounts for the largest proportion increase of all diseases as a cause for endstage renal disease in the United States. Certain populations, i.e., Pima Indians and Mexican and black Americans, have a higher propensity for developing ...
G L, Bakris, J H, Stein
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Diabetic nephropathy occurs in approximately 35% of all diabetic patients, both insulin and non-insulin dependent. It accounts for the largest proportion increase of all diseases as a cause for endstage renal disease in the United States. Certain populations, i.e., Pima Indians and Mexican and black Americans, have a higher propensity for developing ...
G L, Bakris, J H, Stein
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Irish Journal of Medical Science, 1979
Since the original recognition by Kimmelstiel and Wilson in 1936 of a characteristic nodular lesion in diabetic renal glomeruli, no simple relationship has been demonstrated between the structural and functional defects now known to exist in diabetic renal disease.
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Since the original recognition by Kimmelstiel and Wilson in 1936 of a characteristic nodular lesion in diabetic renal glomeruli, no simple relationship has been demonstrated between the structural and functional defects now known to exist in diabetic renal disease.
openaire +3 more sources