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Diabetes mellitus is a common condition and diabetics are prone to develop a spectrum of neuropathic complications ranging from symmetric and diffuse to asymmetric and focal neuropathies that may be associated with significant morbidity. Diabetic sensorimotor polyneuropathy is the most common of these complications, occurring in patients with type 1 ...
Aaron, Izenberg +2 more
openaire +2 more sources
Value of Neurofilament Light Chain as a Biomarker in Peripheral Neuropathy [PDF]
Neurofilament light chain (NfL) has been identified as a biomarker of axonal injury in a variety of central nervous system diseases. The value of NfL as a biomarker in peripheral neuropathy has gained increasing attention.
SUN Xiaoling, HUANG Kaiwei, WAN Xinbei, WU Ying, LI Zhijun
doaj +1 more source
Diagnosing Diabetic Neuropathy: Something Old, Something New [PDF]
There are potentially many ways of assessing diabetic peripheral neuropathy (DPN). However, they do not fulfill U.S. Food and Drug Administration (FDA) requirements in relation to their capacity to assess therapeutic benefit in clinical trials of DPN ...
Ioannis N. Petropoulos +5 more
doaj +1 more source
Corneal Confocal Microscopy Detects Small Fibre Neuropathy in Patients with Upper Gastrointestinal Cancer and Nerve Regeneration in Chemotherapy Induced Peripheral Neuropathy. [PDF]
Published onlineThere are multiple neurological complications of cancer and its treatment. This study assessed the utility of the novel non-invasive ophthalmic technique of corneal confocal microscopy in identifying neuropathy in patients with upper ...
Azmi, S +9 more
core +22 more sources
A large number of peripheral neuropathies, among which are traumatic and diabetic peripheral neuropathies, result from the degeneration of the myelin sheath, a process called demyelination.
Nicolas Tricaud +4 more
doaj +1 more source
Background: This study attempts to evaluate the utility of nerve biopsy in complementing or redirecting clinical diagnosis. Several factors determine the diagnostic utility of nerve biopsy, the most important being pre-biopsy diagnosis, with higher ...
Jitesh Goel +4 more
doaj +1 more source
Corneal confocal microscopy differentiates inflammatory from diabetic neuropathy
Background Immune-mediated neuropathies, such as chronic inflammatory demyelinating polyneuropathy (CIDP) are treatable neuropathies. Among individuals with diabetic neuropathy, it remains a challenge to identify those individuals who develop CIDP ...
Michael Fleischer +9 more
doaj +1 more source
Acute diabetic neuropathy following improved glycaemic control: a case series and review
We present three cases of acute diabetic neuropathy and highlight a potentially underappreciated link between tightening of glycaemic control and acute neuropathies in patients with diabetes.
N Siddique +5 more
doaj +1 more source
An Insight into Potential Pharmacotherapeutic Agents for Painful Diabetic Neuropathy
Diabetes is the 4th most common disease affecting the world’s population. It is accompanied by many complications that deteriorate the quality of life. Painful diabetic neuropathy (PDN) is one of the debilitating consequences of diabetes that effects one-
Zunaira Qureshi +2 more
doaj +1 more source
The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter +2 more
core +1 more source

