Acta Neuropathologica Communications, 2018 Terminal complement complex deposition in endomysial capillaries detected by a C5b-9 immunostain is considered a diagnostic feature for dermatomyositis.
Paul C. Yell +4 more
doaj +1 more source
Aberrant Schwann Cell Lipid Metabolism Linked to Mitochondrial Deficits Leads to Axon Degeneration and Neuropathy [PDF]
, 2013 SummaryMitochondrial dysfunction is a common cause of peripheral neuropathy. Much effort has been devoted to examining the role played by neuronal/axonal mitochondria, but how mitochondrial deficits in peripheral nerve glia (Schwann cells [SCs ...
Gross, Richard W. +7 more
core +1 more source
Evaluating Performance of Machine Learning Models for Diabetic Sensorimotor Polyneuropathy Severity Classification using Biomechanical Signals during Gait [PDF]
arXiv, 2022 Diabetic sensorimotor polyneuropathy (DSPN) is one of the prevalent forms of neuropathy affected by diabetic patients that involves alterations in biomechanical changes in human gait. In literature, for the last 50 years, researchers are trying to observe the biomechanical changes due to DSPN by studying muscle electromyography (EMG), and ground ...
arxiv
Automatic detection of rare pathologies in fundus photographs using few-shot learning [PDF]
Medical Image Analysis, Volume 61, April 2020, 101660, 2019 In the last decades, large datasets of fundus photographs have been collected in diabetic retinopathy (DR) screening networks. Through deep learning, these datasets were used to train automatic detectors for DR and a few other frequent pathologies, with the goal to automate screening.
arxiv +1 more source
Effects of the Low-Level Laser Therapy (LLLT) in the process of healing diabetic foot ulcers [PDF]
Acta Cirúrgica Brasileira, 2015 PURPOSE: To evaluate the effects of the low-level laser therapy applying Laser on the tissue repair in ulcer carriers due to diabetes. METHODS: Sixteen type II diabetic patients, ulcer carriers in the lower limbs, participated in the research from which
Maura Cristina Porto Feitosa +5 more
doaj +1 more source
Deep Learning and Glaucoma Specialists: The Relative Importance of Optic Disc Features to Predict Glaucoma Referral in Fundus Photos [PDF]
Ophthalmology (2019), 2018 Glaucoma is the leading cause of preventable, irreversible blindness world-wide. The disease can remain asymptomatic until severe, and an estimated 50%-90% of people with glaucoma remain undiagnosed. Glaucoma screening is recommended for early detection and treatment.
arxiv +1 more source
Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration [PDF]
, 2015 Diabetic peripheral neuropathy affects up to half of diabetic patients. This neuronal damage leads to sensory disturbances, including allodynia and hyperalgesia.
Arimura +68 more
core +2 more sources
A Novel Model of Cancer-Induced Peripheral Neuropathy and the Role of TRPA1 in Pain Transduction [PDF]
Pain Research and Management, Volume 2017, Article ID 3517207, 2018 Background. Models of cancer-induced neuropathy are designed by injecting cancer cells near the peripheral nerves. The interference of tissue-resident immune cells does not allow a direct contact with nerve fibres which affects the tumor microenvironment and the invasion process. Methods.
arxiv +1 more source
Diabetic Neuropathy: A Position Statement by the American Diabetes Association
Diabetes Care, 2016 Diabetic neuropathies are the most prevalent chronic complications of diabetes. This heterogeneous group of conditions affects different parts of the nervous system and presents with diverse clinical manifestations.
R. Pop-Busui +7 more
semanticscholar +1 more source
Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function [PDF]
, 2011 Mitochondrial dysfunction is a common cause of peripheral neuropathies. While the role of neuron and axonal mitochondria in peripheral nerve disease is well appreciated, whether Schwann cell (SC) mitochondrial deficits contribute to peripheral ...
Baloh, Robert H +5 more
core +2 more sources