Results 1 to 10 of about 878,879 (388)
Nature Reviews Disease Primers, 2019 AbstractDiabetes mellitus is becoming increasingly common worldwide. As this occurs, there will be an increase in the prevalence of known comorbidities from this disorder of glucose metabolism. One of the most disabling adverse comorbidities is diabetic neuropathy.
Eva Feldman +2 more
exaly +11 more sources
Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy
Neural Regeneration Research, 2022 Diabetic neuropathy is a prevalent microvascular complication of diabetes mellitus, affecting nerves in all parts of the body including corneal nerves and peripheral nervous system, leading to diabetic corneal neuropathy and diabetic peripheral ...
Wei Zheng So +6 more
doaj +2 more sources
Advanced age and elevated cholesterol predict diabetic neuropathy in patients with type II diabetes mellitus in Southern Ethiopia [PDF]
Cardiovascular Diabetology. Endocrinology ReportsBackground Diabetic neuropathy is the debilitating most common and expensive complication of diabetes that can cause significant mortality and morbidity, resulting from foot ulceration, lower extremity amputation, and pain that reduces the quality of ...
Fasika Merid +3 more
doaj +2 more sources
Journal of Diabetes Investigation, 2021 Aims/Introduction To examine the prevalence of falls and fractures, and the association with symptoms of diabetic polyneuropathy (DPN) in patients with recently diagnosed type 2 diabetes.
Karolina Snopek Khan +7 more
doaj +1 more source
A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia
iScience, 2023 Summary: Diabetic peripheral neuropathy (DPN) is the most common chronic, progressive complication of diabetes mellitus. The main symptom is sensory loss; the molecular mechanisms are not fully understood.
Mari Suzuki +7 more
doaj +1 more source
Current Treatment Options in Neurology, 2000 There are currently no treatments available (beyond optimal control of hyperglycemia) that arrest or reverse progressive diabetic polyneuropathy. Consultation with a diabetologist is indicated for patients with poorly controlled disease and polyneuropathy. Immunotherapy for diabetic lumbosacral plexopathy has been advocated but is not supported to date
A I, Vinik +3 more
openaire +4 more sources
Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions
Scientific Reports, 2021 Pyruvate functions as a key molecule in energy production and as an antioxidant. The efficacy of pyruvate supplementation in diabetic retinopathy and nephropathy has been shown in animal models; however, its significance in the functional maintenance of ...
Hideji Yako +7 more
doaj +1 more source
Data in Brief, 2021 The accumulation of pathogenic misfolded proteins is believed to be a common mechanism of generation of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and polyglutamine (polyQ) diseases.
Masaki Oba +3 more
doaj +1 more source
Foot and Ankle Clinics, 2006 In this review, an in-depth anatomic and molecular pathogenesis of diabetic neuropathy is provided. Classifications and clinical manifestations of diabetic neuropathy are discussed. The current modalities of treatment and clinical research on this disorder are summarized.
Christopher, Bibbo, Dipak V, Patel
openaire +4 more sources
Clinical spectrum and diagnosis of diabetic neuropathies [PDF]
The Korean Journal of Internal Medicine, 2020 Neuropathy is the most prevalent microvascular complication of diabetes mellitus; it encompasses distal symmetric polyneuropathy, autonomic neuropathy, radiculoplexus neuropathy, mononeuropathy, and treatment-induced neuropathy.
Jeeyoung Oh
doaj +1 more source