Results 11 to 20 of about 845,763 (299)
Seminars in Neurology, 2019 AbstractDiabetes mellitus is becoming increasingly common worldwide. As this occurs, there will be an increase in the prevalence of known comorbidities from this disorder of glucose metabolism. One of the most disabling adverse comorbidities is diabetic neuropathy.
Elina, Zakin +2 more
semanticscholar +10 more sources
Perspectives of glycemic variability in diabetic neuropathy: a comprehensive review
Communications Biology, 2021 Zhang et al. describe metrics for evaluating glycaemic variability (GV) in clinical practice and summarize the role and related mechanisms of GV in diabetic neuropathy, including cardiovascular autonomic neuropathy, diabetic peripheral neuropathy and ...
Xiaochun Zhang +3 more
doaj +2 more sources
Functional and Structural Changes of the Blood-Nerve-Barrier in Diabetic Neuropathy
Frontiers in Neuroscience, 2019 The incidence of diabetes mellitus is approaching global epidemic proportions and should be considered a major health-care problem of modern societies in the twenty-first century.
Mette Richner +9 more
doaj +2 more sources
JAMA Neurology, 2021 Key Points Question Will 10-kHz spinal cord stimulation improve pain relief for patients with painful diabetic neuropathy refractory to medical management? Findings In this randomized clinical trial including 216 patients, there was a significant benefit
E. Petersen +36 more
semanticscholar +1 more source
Brain : a journal of neurology, 2021 Peripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes. Up to half of patients with diabetes develop neuropathy during the course of their disease, which is accompanied by neuropathic pain in to 30-40% of cases ...
T. Jensen +16 more
semanticscholar +1 more source
Inflammatory Mechanisms in the Pathophysiology of Diabetic Peripheral Neuropathy (DN)—New Aspects
International Journal of Molecular Sciences, 2021 The pathogenesis of diabetic neuropathy is complex, and various pathogenic pathways have been proposed. A better understanding of the pathophysiology is warranted for developing novel therapeutic strategies.
P. Baum +4 more
semanticscholar +1 more source
Statistical modeling of diabetic neuropathy: Exploring the dynamics of nerve mortality [PDF]
, 2023 Diabetic neuropathy is a disorder characterized by impaired nerve function and reduction of the number of epidermal nerve fibers per epidermal surface. Additionally, as neuropathy related nerve fiber loss and regrowth progresses over time, the two-dimensional spatial arrangement of the nerves becomes more clustered. These observations suggest that with
arxiv +1 more source
Challenges of neuropathic pain: focus on diabetic neuropathy
Journal of neural transmission, 2020 Neuropathic pain is a frequent condition caused by a lesion or disease of the central or peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain is diabetic neuropathy.
D. Rosenberger +4 more
semanticscholar +1 more source
Current Treatment Options in Neurology, 2000 There are currently no treatments available (beyond optimal control of hyperglycemia) that arrest or reverse progressive diabetic polyneuropathy. Consultation with a diabetologist is indicated for patients with poorly controlled disease and polyneuropathy. Immunotherapy for diabetic lumbosacral plexopathy has been advocated but is not supported to date
A I, Vinik +3 more
openaire +4 more sources
Frontiers in Neuroscience, 2020 Peripheral nerve function is metabolically demanding and nerve energy failure has been implicated in the onset and development of diabetic peripheral neuropathy and neuropathic pain conditions.
Anete Dudele +5 more
doaj +1 more source