Screening for diabetic peripheral neuropathy in resource-limited settings
Background Diabetic neuropathy is the most common microvascular complication of diabetes mellitus and a major risk factor for diabetes-related lower-extremity complications.
Ken Munene Nkonge+2 more
doaj +1 more source
Charcot neuroarthropathy : pathogenesis, diagnosis and medical management [PDF]
Charcot neuroarthropathy (CN) is a progressive degenerative arthropathy which rarely complicates diabetes mellitus. Most commonly, though not exclusively affecting the foot, it seems to be determined by the interaction of neuropathy, osteopaenia and ...
Cachia, Mario J., Vella, Sandro
core
Measuring visual cortical oxygenation in diabetes using functional near-infrared spectroscopy [PDF]
Aims: Diabetes mellitus affects about 6% of the world’s population, and the chronic complications of the disease may result in macro- and micro-vascular changes.
Aitchison, Ross T.+5 more
core +3 more sources
A Novel Model of Cancer-Induced Peripheral Neuropathy and the Role of TRPA1 in Pain Transduction [PDF]
Background. Models of cancer-induced neuropathy are designed by injecting cancer cells near the peripheral nerves. The interference of tissue-resident immune cells does not allow a direct contact with nerve fibres which affects the tumor microenvironment and the invasion process. Methods.
arxiv +1 more source
A review on the investigation of peripheral neuropathy at Mater Dei Hospital [PDF]
The term peripheral neuropathy encompasses a wide range of disorders. The underlying causes of peripheral neuropathy are diverse. It is very difficult to ascertain the incidence of peripheral neuropathy with any degree of certainty, but it is a ...
Aquilina, Josanne+2 more
core
The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons [PDF]
1. Electrotonic responses to 150 ms current pulses were recorded from isolated rat dorsal roots incubated for at least 3 h with either normal (5 mM) or high (25 mM) D-glucose solutions, and with either normal (25 mM) or low (5 mM) bicarbonate ...
Bostock, Hugh+2 more
core +2 more sources
Spotlight on nerves: Portable multispectral optoacoustic imaging of peripheral nerve vascularization and morphology [PDF]
Various morphological and functional parameters of peripheral nerves and their vascular supply are indicative of pathological changes due to injury or disease. Based on recent improvements in optoacoustic image quality, we explore the ability of multispectral optoacoustic tomography, in tandem with ultrasound imaging (OPUS), to investigate the vascular
arxiv
Is resistance to ischaemia of motor axons in diabetic subjects due to membrane depolarization? [PDF]
The reasons for the resistance to ischaemia of peripheral nerves in diabetics are not well understood. We have now explored whether axonal depolarization underlies this phenomenon, as has previously been proposed.
Baker+34 more
core +1 more source
Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible technique that quantifies small nerve fibres. We have compared the diagnostic capability of CCM against a range of established measures of nerve damage in patients with ...
U. Alam+10 more
semanticscholar +1 more source
High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
Aim of the study: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness ...
Kunwarpal Singh+2 more
doaj +1 more source