Results 161 to 170 of about 54,528 (266)

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska   +8 more
wiley   +1 more source

Adverse Outcomes and Associated Factors Among Children and Youths With Diabetes Mellitus in East Africa: A Systematic Review and Meta‐Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To identify adverse outcomes and factors associated with diabetes mellitus among children and youths in East Africa. Design This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines.
Chalie Marew Tiruneh   +3 more
wiley   +1 more source

Dapagliflozin Preserves Peripheral Nerve Structure and Reduces Neuropathic Damage in Streptozotocin-Induced Diabetic Peripheral Neuropathy. [PDF]

open access: yesInt J Mol Sci
Țucă AM   +10 more
europepmc   +1 more source

Electrophysiological diagnosis using the coefficient of variation of R‐R intervals and a point‐of‐care nerve conduction device is highly correlated to the diagnosis of diabetic polyneuropathy using conventional electromyographs

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction While treatment for diabetic polyneuropathy (DPN) is still developing, progress has stagnated. The alignment between pathological neurodegeneration in DPN and patients' subjective symptoms is often low, yet these symptoms are frequently used for diagnosis.
Tatsuhito Himeno   +14 more
wiley   +1 more source

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi   +8 more
wiley   +1 more source

Impact of glycemic variability on early detection of sudomotor dysfunction: Implications for early intervention and personalized treatment

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Background This study investigates the impact of glycemic variability on sudomotor dysfunction in type 2 diabetes mellitus. Methods A total of 206 type 2 diabetes mellitus patients and 34 healthy controls were included. Sweat function (SF) was assessed using electrochemical conductance of hands (HESC) and feet (FESC).
Yang Ou   +4 more
wiley   +1 more source

Role of nerve ultrasound and shear wave elastography in stratified diagnosis of diabetic peripheral neuropathy. [PDF]

open access: yesMedicine (Baltimore)
Lai ZH   +7 more
europepmc   +1 more source

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