Results 81 to 90 of about 150,695 (362)

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani, Hao Li, Panpan Guo, Qiulin Zhang, Mahmoud M. Abouelfetouh, Mingxing Ding, Yi Ding   +6 more
wiley   +1 more source

The correlation between vitamin D deficiency and the severity of painful diabetic neuropathy in patients with type 2 diabetes mellitus (T2DM)

Jurnal Gizi Klinik Indonesia, 2020
Background: Diabetes and its complications are the major burden health problem worldwide, and diabetic neuropathy is one of the major complications. Vitamin D levels found to be significantly lower in people with painful diabetic peripheral neuropathy ...
Rizaldy Taslim Pinzon, Putu Clara Shinta Gelgel   +1 more
doaj   +1 more source

Deprenyl, an old drug with new anticancer potential: Mini review [PDF]

arXiv, 2021
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv  

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

Animal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera, Abeer Abdullah Alghamdi, Mesfer Al‐Shahrani, Reem M. Al‐Gahtani, Bashayer Saad Alghamdi, Gaffar Sarwar Zaman, Mohammed Abdul Rasheed, Hassan Al‐Shehri, Lana Al‐qhtani, Syed Parween Ali, Umme Hani, Talha Bin Emran   +11 more
wiley   +1 more source

Iron role paradox in nerve degeneration and regeneration [PDF]

Bolandghamat, S., & Behnam-Rassouli, M. (2024). Iron role paradox in nerve degeneration and regeneration. Physiological Reports, 12, e15908
Iron accumulates in the neural tissue during peripheral nerve degeneration. Some studies have already been suggested that iron facilitates Wallerian degeneration (WD) events such as Schwann cell de-differentiation. On the other hand, intracellular iron levels remain elevated during nerve regeneration and gradually decrease.
arxiv   +1 more source

Evaluating Performance of Machine Learning Models for Diabetic Sensorimotor Polyneuropathy Severity Classification using Biomechanical Signals during Gait [PDF]

arXiv, 2022
Diabetic sensorimotor polyneuropathy (DSPN) is one of the prevalent forms of neuropathy affected by diabetic patients that involves alterations in biomechanical changes in human gait. In literature, for the last 50 years, researchers are trying to observe the biomechanical changes due to DSPN by studying muscle electromyography (EMG), and ground ...
arxiv  

Trends in gabapentinoid prescribing: A nationwide Danish drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Aims Pregabalin and gabapentin are increasingly used for pain and other conditions. Concerns exist about overuse as well as potential misuse and abuse. To guide rational prescribing practices, we provide detailed nationwide data on the use of gabapentinoids in Denmark.
Anton Pottegård, Lotte Rasmussen, Morten Olesen, Anne Mette Skov Sørensen, Zandra Nymand Ennis, Joseph Kane, Sarah Baxter, Blánaid Hicks   +7 more
wiley   +1 more source

The prevalence of peripheral neuropathy among the patients with diabetes in Pakistan: a systematic review and meta-analysis

Scientific Reports, 2023
The most frequent complication of diabetes is peripheral neuropathy. The estimated prevalence of peripheral neuropathy in people with diabetes varies substantially between published studies in Pakistan.
Sohail Akhtar, Fazal Hassan, Seda Rakhshanda Saqlain, Aqsa Ali, Sardar Hussain   +4 more
doaj   +1 more source

Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice

Diabetes, 2019
Diabetic peripheral neuropathy (DPN) is the most common complication in both type 1 and type 2 diabetes, but any treatment toward the development of DPN is not yet available.
Yalan Cheng, Jun Liu, Yi Luan, Zhiyuan Liu, Hejin Lai, Wuling Zhong, Yale Yang, Huimin Yu, Ning Feng, Hui Wang, Rui Huang, Zhishui He, Menghong Yan, Fang Zhang, Yan-Gang Sun, Hao Yin, Feifan Guo, Q. Zhai   +17 more
semanticscholar   +1 more source

Automatic detection of rare pathologies in fundus photographs using few-shot learning [PDF]

Medical Image Analysis, Volume 61, April 2020, 101660, 2019
In the last decades, large datasets of fundus photographs have been collected in diabetic retinopathy (DR) screening networks. Through deep learning, these datasets were used to train automatic detectors for DR and a few other frequent pathologies, with the goal to automate screening.
arxiv   +1 more source