Results 181 to 190 of about 437,591 (276)

Intermittent fasting in diabetic retinopathy: microbiome modulation, mechanisms, and clinical insights. [PDF]

Cardiovasc Endocrinol Metab
Ahmadzadeh O, Ghafouri D, Hoseinpour A, Motlagh SM, Shabani A, Shadnoush M, Samani P, Mirzaei A, Javid Z, Ghorbani E, Zolfaghari G, Arabgol S, Darvish P, Jafari Karegar S.   +13 more
europepmc   +1 more source

Randomised Clinical Trial to Evaluate the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in X‐Linked Retinoschisis: The AXIS Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This trial aimed to evaluate the efficacy of oral acetazolamide in reducing cystoid fluid collections (CFC) and improving visual function in patients with X‐linked retinoschisis (XLRS). Methods In this investigator‐initiated, single centre, open‐label, randomised controlled trial, XLRS patients aged ≥ 12 years with fovea‐involving ...
Jonathan Hensman, Hind Almushattat, Roselie M. H. Diederen, Tien‐En Tan, Peilun Dai, Coen de Vente, Daniel S. W. Ting, Maria M. van Genderen, Jeannette Ossewaarde‐van Norel, Redmer van Leeuwen, Martha J. H. Tjon‐Fo‐Sang, Clara I. Sánchez, M. Dominik Fischer, Maximilian Pfau, Jos W. R. Twisk, Camiel J. F. Boon   +15 more
wiley   +1 more source

The gut-retina axis in diabetic retinopathy: a new paradigm for pathogenesis and therapeutic intervention. [PDF]

Front Immunol
Tong B, Wang M, Yang X, Liu L.
europepmc   +1 more source

VEGF‐A Antisense Oligonucleotide Therapy Inhibits Corneal Neovascularisation and Enhances Graft Survival in Murine High‐Risk Corneal Transplantation

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate, for the first time, whether an unconjugated VEGF‐A antisense oligonucleotide (ASO) can inhibit corneal neovascularisation and improve graft survival in a murine high‐risk corneal transplantation model. Methods A suture‐induced corneal neovascularisation model was established in BALB/c mice, followed by high‐risk ...
Wei Zhang, Christian Weile, Christoph Ullmer, Sascha Fauser, Felix Bock, Claus Cursiefen   +5 more
wiley   +1 more source

Diabetic Retinopathy Detection: AI Models and Approaches. [PDF]

J Ophthalmol
Madi MMM, Farr PC, Bester D.
europepmc   +1 more source

Correcting Axial Length‐Related Magnification Errors in Optical Coherence Tomography Angiography Improves Machine Learning Classification Performance in High Myopia

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To determine whether axial length‐related magnification correction in optical coherence tomography angiography (OCTA) improves machine learning classification of high myopia and resolves inconsistencies in the values and discriminatory power of OCTA microvascular metrics.
Danuta M. Sampson, Mila Yue Zhang, Hemn Baghban Jaldian, Madeleine S. Torcasso, Gavrielle R. Untracht, Jocelyn J. Drinkwater, Mei Zhao, David D. Sampson, Andrew Lam, Fred K. Chen   +9 more
wiley   +1 more source

Suppression of Retinal Neovascularisation by Tetrahedral Framework Nucleic Acids‐Resveratrol Via Dual Anti‐Angiogenesis and Anti‐Inflammation

Cell Proliferation, EarlyView.
Resveratrol‐loaded tetrahedral framework nucleic acids (tFNAs‐RSV) enable concurrent anti‐angiogenic and anti‐inflammatory therapy, enhancing ocular delivery and bioactivity. In hypoxia‐induced retinal neovascularisation, tFNAs‐RSV reduce neovascular lesions, vascular leakage and inflammatory infiltration by suppressing HIF‐1, p38 MAPK and NF‐κB p65 ...
Yili Jin, Tao Cai, Junyang Huang, Li Chen, Yi Lin, Jingying Liu, You Wang, Xiaoyan Ding   +7 more
wiley   +1 more source

Nailfold capillaroscopy in diabetic retinopathy: microvascular insights, clinical value, and translational challenges - a narrative review. [PDF]

Front Endocrinol (Lausanne)
Zhou YM, Cen LS.
europepmc   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source