Results 61 to 70 of about 754,924 (328)

Indian Diabetic Retinopathy Image Dataset (IDRiD): A Database for Diabetic Retinopathy Screening Research

International Conference on Data Technologies and Applications, 2018
Diabetic Retinopathy is the most prevalent cause of avoidable vision impairment, mainly affecting the working-age population in the world. Recent research has given a better understanding of the requirement in clinical eye care practice to identify ...
Prasanna Porwal, S. Pachade, Ravi Kamble, M. Kokare, Girish Deshmukh, Vivek Sahasrabuddhe, F. Mériaudeau   +6 more
semanticscholar   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Relationship between Stage of Diabetic Retinopathy and Pulse Wave Velocity in Japanese Patients with Type 2 Diabetes

Journal of Diabetes Research, 2013
Objectives. We investigated the relationship between the stage of diabetic retinopathy and pulse wave velocity (PWV). Methods. This was a cross-sectional study of 689 patients (406 men and 283 women) with type 2 diabetes who were admitted to our hospital
Kumiko Tanaka, Toshihide Kawai, Yoshifumi Saisho, Shu Meguro, Kana Harada, Yuka Satoh, Kaori Kobayashi, Kei Mizushima, Takayuki Abe, Hiroshi Itoh   +9 more
doaj   +1 more source

Correlation between Serum Sialic Acid Level and frequent risk factors of Diabetic Retinopathy

مجلة كلية الطب, 2011
Background: Diabetic retinopathy is an important complication of diabetes mellitus. It is supposed that elevated sialic acid in diabetes mellitus plays an important role in diabetic retinopathy.
Nada F. Rashid
doaj   +1 more source

Diabetic Retinopathy Detection Using Prognosis of Microaneurysm and Early Diagnosis System for Non-Proliferative Diabetic Retinopathy Based on Deep Learning Algorithms

IEEE Access, 2020
Predicting the presence of Microaneurysms in the fundus images and the identification of diabetic retinopathy in early-stage has always been a major challenge for decades.
Lifeng Qiao, Ying Zhu, Hui Zhou
semanticscholar   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Awareness and knowledge of diabetic retinopathy in diabetic patients at a General Hospital in Northwest Ethiopia

SAGE Open Medicine, 2021
Objective: Diabetic retinopathy is an evident complication of diabetes on eye and contributes for significant portion of blindness worldwide. In Ethiopia, data are lacking on awareness and knowledge of diabetic retinopathy in diabetic patients.
Getasew Alemu Mersha, Yezinash Addis Alimaw, Asamere Tsegaw Woredekal, Aragaw Kegne Assaye, Tarekegn Chekilie Zeleke   +4 more
doaj   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

Advanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding, Yuhuan Jia, Lin Liu, Wen Wang, Danxia Zhou, Zheng Zhou, Likun Yang, Xinyi Chen, Di Chen, Yan Mao, Liwei Xiao, Cai‐Zhi Liu, Zhen‐Yu Du, Yujing Yin, Qiqi Guo, Zongchao Sun, Kai Ge, Tingting Fu, Hai‐Long Piao, Zhenji Gan   +19 more
wiley   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Dissociation of blood interleukin spectrum in the patients with accelerated aging and diabetic retinopathy

Медицинская иммунология
Diabetic retinopathy is a common complication of diabetes mellitus, especially, in elderly persons, due to growth of this population in many countries. However, involvement of immune system in patients with diabetic retinopathy and into the aging process
N. M. Agarkov, I. V. Lev, E. A. Voronina
doaj   +1 more source