Results 61 to 70 of about 228,603 (338)

Dissociation of blood interleukin spectrum in the patients with accelerated aging and diabetic retinopathy

Медицинская иммунология
Diabetic retinopathy is a common complication of diabetes mellitus, especially, in elderly persons, due to growth of this population in many countries. However, involvement of immune system in patients with diabetic retinopathy and into the aging process
N. M. Agarkov, I. V. Lev, E. A. Voronina
doaj   +1 more source

Vitamin Status as a Determinant of Serum Homocysteine Concentration in Type 2 Diabetic Retinopathy

Journal of Diabetes Research, 2014
We investigated the association of serum homocysteine levels and vitamin status with type 2 diabetic retinopathy. This study included 65 patients with and 75 patients without diabetic retinopathy.
Pandelis Fotiou, Athanasios Raptis, George Apergis, George Dimitriadis, Ioannis Vergados, Panagiotis Theodossiadis   +5 more
doaj   +1 more source

Artificial intelligence using deep learning to screen for referable and vision-threatening diabetic retinopathy in Africa: a clinical validation study

The Lancet: Digital Health, 2019
Summary: Background: Radical measures are required to identify and reduce blindness due to diabetes to achieve the Sustainable Development Goals by 2030.
Valentina Bellemo, MSc, Zhan W Lim, PhD, Gilbert Lim, PhD, Quang D Nguyen, BEng, Yuchen Xie, MScPH, Michelle Y T Yip, BA, Haslina Hamzah, BSc, Jinyi Ho, DFST, Xin Q Lee, BSc (Hons), Wynne Hsu, PhD, Mong L Lee, PhD, Lillian Musonda, MD, Manju Chandran, FRCOphth, Grace Chipalo-Mutati, FCOphth (ECSA), Mulenga Muma, FCOphth (ECSA), Gavin S W Tan, MD, Sobha Sivaprasad, FRCOphth, Geeta Menon, FRCOphth, Tien Y Wong, MD, Daniel S W Ting, MD   +19 more
doaj   +1 more source

Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications

Advanced Materials, EarlyView.
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi, Chunyao Wang, Xuan Mei, Ben Zhang, Junxi Wu, Rylie A. Green, Yu Shrike Zhang, Wenmiao Shu   +7 more
wiley   +1 more source

Non-Perfusion Area Index for Prognostic Prediction in Diabetic Retinopathy

Life, 2022
Fundus fluorescent angiography is a standard examination in Japan that can directly visualize the circulatory failure in diabetic retinopathy but is not used in Western countries.
Yoshiko Ofuji, Yusaku Katada, Yohei Tomita, Norihiro Nagai, Hideki Sonobe, Kazuhiro Watanabe, Hajime Shinoda, Yoko Ozawa, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara   +10 more
doaj   +1 more source

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

Advanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv, Juzheng Yuan, Zhe Ruan, Ya‐nan Dou, Hongchen Zhang, Xiaowei Fei, Leiying Chen, Zehan Zhang, Kai Yang, Xiuquan Wu, Zhou Fei, Fei Fei   +11 more
wiley   +1 more source

Usefulness of corneal esthesiometry for screening diabetic retinopathy

Revista de Saúde Pública, 2003
OBJECTIVE: To assess the usefulness of corneal esthesiometry for screening diabetic retinopathy. METHODS: A cross-sectional study was carried out comprising 575 patients attending a diabetic retinopathy-screening program in the city of São Paulo. Corneal
Alvarenga Lênio Souza, Martins Elisabeth Nogueira, Grottone Gustavo Teixeira, Morales Paulo Henrique Ávila, Paranhos Jr Augusto, Freitas Denise de, Scarpi Marinho Jorge   +6 more
doaj   +3 more sources

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

Advanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding, Yuhuan Jia, Lin Liu, Wen Wang, Danxia Zhou, Zheng Zhou, Likun Yang, Xinyi Chen, Di Chen, Yan Mao, Liwei Xiao, Cai‐Zhi Liu, Zhen‐Yu Du, Yujing Yin, Qiqi Guo, Zongchao Sun, Kai Ge, Tingting Fu, Hai‐Long Piao, Zhenji Gan   +19 more
wiley   +1 more source

Glycocalyx Degradation in Retinal and Choroidal Capillary Endothelium in Rats with Diabetes and Hypertension [PDF]

, 2010
Endothelial glycocalyx (GCX) has been reported as a protective factor for vascular endothelial cells (VEC) in diabetes and hypertension. However, the involvement of GCX impairment in ocular vasculopathy remains unclear.
Kumase, Fumiaki, Mohri, Satoshi, Morizane, Yuki, Ohtsuka, Aiji, Ohtsuki, Hiroshi, Takasu, Ippei   +5 more
core   +1 more source

Ischemia Modified Albumin Levels in Diabetes Mellitus Patients with and without Diabetic Retinopathy

Journal of Islamic International Medical College, 2021
Objective: To determine and compare the levels of ischemia modified albumin (IMA) in healthy individuals, diabetes without retinopathy, and diabetic having no proliferative and proliferative retinopathy.
Sana Rasheed Chaudhry , Muniza Saeed , Zunnera Rashid Chaudhry , Komal Iqbal , Erum Rashid , Faiza Rasheed
doaj