Results 71 to 80 of about 203,197 (289)

Cost-effectiveness of ranibizumab in treatment of diabetic macular oedema (DME) causing visual impairment : evidence from the RESTORE trial [PDF]

, 2012
Background/aims To evaluate the cost-effectiveness of ranibizumab as either monotherapy or combined with laser therapy, compared with laser monotherapy, in the treatment of diabetic macular oedema (DME) causing visual impairment from a UK healthcare ...
Mitchell, Paul, Annemans, Lieven, Gallagher, Meghan, Hasan, Rafiq, Thomas, Simu, Gairy, Kerry, Knudsen, Martin, Onwordi, Henrietta   +7 more
core   +2 more sources

Tree shrew model of early diabetic retinopathy reveals microvascular dysfunction and identifies phosphoserine aminotransferase 1 as a novel therapeutic target

Animal Models and Experimental Medicine, EarlyView.
We developed an animal model of early diabetic retinopathy (DR) in the tree shrew by feeding a high‐fat and high‐sugar diet in combination with STZ. Physiological and biochemical index detection, hematoxylin and eosin staining, and transmission electron microscopy were performed to examine DR.
Min Qiu, Shurui Huo, Wenguang Wang, Na Li, Qingwei Zeng, Xiaomei Sun, Jiejie Dai, Pinfen Tong, Yuanyuan Han, Ling Zhao, Caixia Lu   +10 more
wiley   +1 more source

Dry Eye in Patients With Diabetic Retinopathy: A Clinical Study

Delhi Journal of Ophthalmology, 2017
Purpose: To study tear film changes in patients of Type 2 diabetes mellitus with and without diabetic retinopathy. Method: A hospital based, cross sectional, observational study including 40 patients of Type 2 diabetes mellitus with diabetic retinopathy ...
Geetika Khurana, Deeksha Khurana, Rajesh Jain   +2 more
doaj   +1 more source

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source

Vitamin Status as a Determinant of Serum Homocysteine Concentration in Type 2 Diabetic Retinopathy

Journal of Diabetes Research, 2014
We investigated the association of serum homocysteine levels and vitamin status with type 2 diabetic retinopathy. This study included 65 patients with and 75 patients without diabetic retinopathy.
Pandelis Fotiou, Athanasios Raptis, George Apergis, George Dimitriadis, Ioannis Vergados, Panagiotis Theodossiadis   +5 more
doaj   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source

Diabetic Retinopathy Analysis [PDF]

BioMed Research International, 2005
Diabetic retinopathy is one of the common complications of diabetes. Unfortunately, in many cases the patient is not aware of any symptoms until it is too late for effective treatment. Through analysis of evoked potential response of the retina, the optical nerve, and the optical brain center, a way will be paved for early diagnosis of diabetic ...
Sivakumar, R., Ravindran, G., Muthayya, M., Lakshminarayanan, S., Velmurughendran, C. U.   +4 more
openaire   +2 more sources

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova, Yoana Lilova, Alexander Oscar, Alina Levi, Maria Kamusheva, Guenka Petrova   +5 more
wiley   +1 more source

Ischemia Modified Albumin Levels in Diabetes Mellitus Patients with and without Diabetic Retinopathy

Journal of Islamic International Medical College, 2021
Objective: To determine and compare the levels of ischemia modified albumin (IMA) in healthy individuals, diabetes without retinopathy, and diabetic having no proliferative and proliferative retinopathy.
Sana Rasheed Chaudhry , Muniza Saeed , Zunnera Rashid Chaudhry , Komal Iqbal , Erum Rashid , Faiza Rasheed
doaj  

A Clinical Study of Diabetic Retinopathy

Journal of Nepal Medical Association, 2003
A clinical study of diabetic retinopathy was conducted from March- May 2002 to diagnose a patient’s diabetic retinopathy level and identify eyes of proliferative diabetic retinopathy and maculopathy so that these patients could get appropriate and timely
KJD Karki
doaj   +1 more source