Results 271 to 280 of about 45,123 (293)
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Diacylglycerol kinases: at the hub of cell signalling
Biochemical Journal, 2007DGKs (diacylglycerol kinases) are members of a unique and conserved family of intracellular lipid kinases that phosphorylate DAG (diacylglycerol), catalysing its conversion into PA (phosphatidic acid). This reaction leads to attenuation of DAG levels in the cell membrane, regulating a host of intracellular signalling proteins that have evolved the ...
Isabel, Mérida +2 more
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Diacylglycerol Kinases: Regulation and Signaling Roles
Thrombosis and Haemostasis, 2002SummaryDiacylglycerol kinases (DGKs) are thought to attenuate diacylglycerol signals by converting diacylglycerol to phosphatidic acid. The nine mammalian diacylglycerol kinases that have been identified are widely expressed, but each isoform has a unique tissue and subcellular distribution.
Matthew K, Topham, Stephen M, Prescott
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Inhibition of diacylglycerol kinases as a physiological way to promote diacylglycerol signaling
Advances in Biological Regulation, 2014Diacylglycerol is a key regulator of cell physiology, controlling the membrane recruitment and activation of signaling molecules. Accordingly, diacylglycerol generation and metabolism are strictly controlled, allowing for localized regulation of its concentration.
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Regulation of diacylglycerol kinase by phosphorylation
Advances in Biological Regulation, 2012Y, Shirai, M, Ikeda, N, Saito
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Regulation and Functions of Diacylglycerol Kinases
Chemical Reviews, 2011Yulia V, Shulga +2 more
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Regulation of ‘signalling diacylglycerol’ in cells: the importance of diacylglycerol kinase
Biochemical Society Transactions, 1996M N, Hodgkin +3 more
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