Results 71 to 80 of about 5,439,941 (291)

Computer-assisted Medical Decision-making System for Diagnosis of Urticaria

MDM Policy & Practice, 2016
Background: Urticaria is a common allergic disease that affects all age groups. Allergic disorders are diagnosed at allergy testing centers using skin tests. Though skin tests are the gold standard tests for allergy diagnosis, specialists are required to
Jabez J. Christopher BE, ME, Harichandran Khanna Nehemiah BE, ME, PhD, Kannan Arputharaj ME, PhD, George L. Moses MSc, PhD   +3 more
doaj   +1 more source

Automated Detection Algorithm of Breast Masses in Three-Dimensional Ultrasound Images [PDF]

Healthcare Informatics Research, 2016
ObjectivesWe propose an automatic breast mass detection algorithm in three-dimensional (3D) ultrasound (US) images using the Hough transform technique.MethodsOne hundred twenty-five cropped images containing 68 benign and 60 malignant masses are acquired
Ji-Wook Jeong, Donghoon Yu, Sooyeul Lee, Jung Min Chang   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Accuracy and Precision in Computer-Assisted Methods for Orthopaedic Surgery

, 2015
This chapter reviews the major approaches to the definition of bone cutting accuracy in the field of computer-assisted orthopaedic surgery. The first part of the chapter reviews the different concepts of accuracy found in literature, from localization in
Federico E. Milano, Cartiaux, Olivier, Milano, Federico, Olivier Cartiaux   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Results of Machine Learning Applications in the Study of COVID-19 Associated Cardiopulmonary Pathology Using Computed Tomography Data

Innovative Biosystems and Bioengineering
Background. The COVID-19 pandemic, caused by SARS-CoV-2, has significantly impacted global health, emphasizing the importance of efficient diagnostic methods.
Ievgen Nastenko, Mykola Linnik, Maksym Honcharuk, Illia Davydovych, Viktoriia Lutchenko, Vitali Babenko, Liudmyla Dolinchuk   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Estimation and Evaluation of New Features from Phonocardiogram for Detecting Cardiovascular Abnormalities

مجله دانشکده پزشکی اصفهان, 2019
Background: In the world, cardiovascular diseases are the major cause of death, as 31% of global mortality is from them. Due to problems such as the lack of technologies such as echocardiography, and limited access to cardiologists in deprived areas ...
Mahdi Nourian-Zavareh, Saeed Kermani, Mohammad Hashemi-Jazi, Maryam Samieinasab   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Time to growth detected by computer-assisted-diagnosis and visual comparison.

, 2019
(a–c) Axial FLAIR MRI scans of a patient in the clinical progression group, diagnosed with an oligo, whose tumor volumes are shown in Fig 2B, at baseline (a), the time point of growth detection by computer-assisted diagnosis (b), and the time point of ...
Paula Province Warren (6743564), Markus Bredel (6743567), John Fiveash (4637791), Andrew DeAtkine (6743552), Elizabeth Coffee (6743555), Louis B. Nabors (6743576), Xiaosi Han (3375371), Nidhal Bouaynaya (6743573), Elias Khayat (6743558), Asim K. Bag (6743561), James Markert (6743570), Hassan M. Fathallah-Shaykh (240026)   +11 more
core   +1 more source