Results 91 to 100 of about 7,065,714 (283)

Toward a Differential Diagnosis of Hidden Hearing Loss in Humans

open access: yesPLoS ONE, 2016
Recent work suggests that hair cells are not the most vulnerable elements in the inner ear; rather, it is the synapses between hair cells and cochlear nerve terminals that degenerate first in the aging or noise-exposed ear.
M. C. Liberman   +4 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Extra medullar Granulocytic sarcoma: a case report of an exceptional localization [PDF]

open access: yes, 2020
Granulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases.
Khaled, Rahal   +5 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Reliability of the thyroid stimulating hormone receptor antibodies level determination in diagnosing and prognosing of immunogenic hyperthyroidism [PDF]

open access: yesVojnosanitetski Pregled, 2009
Background/Aim. Graves disease (GD) is defined as hyperthyroidism with diffuse goiter caused by immunogenic disturbances. Antibodies to the thyroid stimulating hormone (TSH) receptors of thyroid gland (TRAb) have crucial pathogenetic importance in the ...
Aleksić Aleksandar Z.   +3 more
doaj   +1 more source

Case report : Williams-Campbell syndrome [PDF]

open access: yes, 2009
Background: Williams-Campbell syndrome is a rare type of bronchiectasis that is due to deficiency or absence of cartilage in the fourth- to sixth-order bronchi.
Bestry, Iwona   +3 more
core  

Melanoma mimicking malignant peripheral nerve sheath tumor with spread to the cerebellopontine angle: Utility of next-generation sequencing in diagnosis [PDF]

open access: yes, 2018
Cutaneous spindle cell malignancy is associated with a broad differential diagnosis, particularly in the absence of a known primary melanocytic lesion.
Birinyi, Paul   +6 more
core   +3 more sources

Cryptosporidium Infection: Epidemiology, Pathogenesis, and Differential Diagnosis

open access: yesEuropean Journal of Microbiology & Immunology, 2019
Cryptosporidium is a protozoan that infects a wide variety of vertebrates, including humans, causing acute gastroenteritis. The disease manifests with abdominal pain and diarrhea similar to that of choleric infection.
E. Gerace   +2 more
semanticscholar   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, Volume 19, Issue 12, Page 3806-3820, December 2025.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Algorithm for diagnosis of primary vasculitides

open access: yesJornal Vascular Brasileiro, 2019
Primary vasculitides are diseases with a wide variety of anatomical, clinical, radiological, and laboratory presentations. Primary vasculitides are difficult to diagnose because of the complexity of clinical presentation, which may lead to delayed ...
Alexandre Sacchetti Bezerra   +3 more
doaj   +1 more source

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