Results 81 to 90 of about 426,653 (250)

CSA-Net: Channel and Spatial Attention-Based Network for Mammogram and Ultrasound Image Classification

open access: yesJournal of Imaging
Breast cancer persists as a critical global health concern, emphasizing the advancement of reliable diagnostic strategies to improve patient survival rates.
Osama Bin Naeem, Yasir Saleem
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Research on the application value of blood plasma autofluorescence spectroscopy model constructed by machine learning algorithms in identifying the types of post-operative kidney transplantation injury

open access: yesPhotodiagnosis and Photodynamic Therapy
s: Background: This study aimed to assess the value of blood plasma autofluorescence spectroscopy in classifying renal injury after renal transplantation.
Lijuan Wu   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Deep learning for FDG-PET classification in patients with Alzheimer’s disease, dementia with Lewy bodies and their mixed pathology: a solution for diagnostic heterogeneity

open access: yesFrontiers in Aging Neuroscience
IntroductionMixed pathology of Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) are frequently observed in patients with cognitive impairment, and complicate clinical diagnosis.
Seonggyu Kim   +8 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Rapid diagnostic algorithms as a screening tool for tuberculosis: an assessor blinded cross-sectional study.

open access: yesPLoS ONE, 2012
BackgroundA major obstacle to effectively treat and control tuberculosis is the absence of an accurate, rapid, and low-cost diagnostic tool. A new approach for the screening of patients for tuberculosis is the use of rapid diagnostic classification ...
Franz Ratzinger   +10 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Value Analysis of MRI Habitat Analysis Combined Model in the Diagnosis of Ovarian Tumors

open access: yesTechnology in Cancer Research & Treatment
Objective This study aimed to investigate the clinical diagnostic performance of a combined classification model incorporating magnetic resonance imaging (T1WI-CE) habitat and human epididymis protein 4 (HE4) for differentiating borderline ovarian tumors
Junying Wang   +4 more
doaj   +1 more source

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