Results 121 to 130 of about 909,683 (265)

Hypolacrimia and Alacrimia as Diagnostic Features for Genetic or Congenital Conditions. [PDF]

Invest Ophthalmol Vis Sci, 2022
Willems M, Wells CF, Coubes C, Pequignot M, Kuony A, Michon F.   +5 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

CIDP With and Without Monoclonal Gammopathy of Undetermined Significance (MGUS): Comparison of Clinical Phenotype, Diagnostic Features, and Treatment Response. [PDF]

J Peripher Nerv Syst
van Veen R, Baars AE, van Doorn IN, Michael M, Bus SRM, Broers MC, van der Pol WL, Van Doorn PA, Drenthen J, Verhamme C, Vos JMI, van Schaik IN, Goedee HS, Wieske L, Jacobs BC, Eftimov F, ICOS Consortium.   +16 more
europepmc   +1 more source

Diagnostic features of type II fibrinoid leukodystrophy (Alexander disease) in a juvenile Beagle dog. [PDF]

J Vet Intern Med, 2023
Vandenberghe H, Baiker K, Nye G, Escauriaza L, Roberts E, Granger N, Reeve L.   +6 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Clinical and Diagnostic Features of Feline Epilepsy: Distribution of Seizure Types and Associated Factors. [PDF]

Animals (Basel)
Jankauskas M, Tamosauskaite J, Gradeckienė A, Čižinauskas S, Kvitka D, Riškevičienė V.   +5 more
europepmc   +1 more source

Brief Test of Olfactory Dysfunction Based on Diagnostic Features of Specific Odors in Early-Stage Alzheimer Disease. [PDF]

Med Sci Monit, 2023
Audronyte E, Sutnikiene V, Pakulaite-Kazliene G, Kaubrys G.   +3 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Pre-Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case-Control Study. [PDF]

Ann Clin Transl Neurol
Tank P, Jacobs BM, Bestwick J, Dobson R.
europepmc   +1 more source

Machine learning approach to screen new diagnostic features of adamantinomatous craniopharyngioma and explore personalised treatment strategies. [PDF]

Transl Pediatr, 2023
Wu J, Qin C, Fang G, Shen L, Li M, Lu B, Li Y, Yao X, Fang D.   +8 more
europepmc   +1 more source