Results 141 to 150 of about 909,683 (265)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Electrocutions in Free-Ranging Platyrrhine Nonhuman Primates: Diagnostic Features for a Threatening Condition. [PDF]

open access: yesAm J Primatol
Barros RM   +8 more
europepmc   +1 more source

Diagnostic Features for Human Categorisation of Adult and Child Faces. [PDF]

open access: yesFront Psychol, 2021
Faghel-Soubeyrand S   +4 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Evaluation of the diagnostic features and clinical course of COVID-19 vaccine-associated subacute thyroiditis. [PDF]

open access: yesHormones (Athens), 2022
Bostan H   +9 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Microbial diagnostic features identified across populations possess potential antitumor properties in breast cancer. [PDF]

open access: yesmSystems
Zhou M   +12 more
europepmc   +1 more source

Bowel Obstruction due to Shiitake Mushrooms: Diagnostic Features on Computed Tomography. [PDF]

open access: yesIntern Med, 2022
Miyagishima D   +10 more
europepmc   +1 more source

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