Results 181 to 190 of about 1,030,441 (312)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Pre-Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case-Control Study. [PDF]

Ann Clin Transl Neurol
Tank P, Jacobs BM, Bestwick J, Dobson R.
europepmc   +1 more source

Brief Test of Olfactory Dysfunction Based on Diagnostic Features of Specific Odors in Early-Stage Alzheimer Disease. [PDF]

Med Sci Monit, 2023
Audronyte E, Sutnikiene V, Pakulaite-Kazliene G, Kaubrys G.   +3 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease.

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, MacKay, A, Thompson, AG, Porter, MC, Rudge, P, Collinge, J, Lowe, J, Mead, S, Uphill, J, Lukic, A   +9 more
core  

Diagnostic Features and Prescription Rules of Influenza-Like Illnesses in Traditional Chinese Medicine: A Data Mining Approach. [PDF]

J Multidiscip Healthc
Liu X, Chang R, Feng S, Deng G, Zhou L.
europepmc   +1 more source

Machine learning approach to screen new diagnostic features of adamantinomatous craniopharyngioma and explore personalised treatment strategies. [PDF]

Transl Pediatr, 2023
Wu J, Qin C, Fang G, Shen L, Li M, Lu B, Li Y, Yao X, Fang D.   +8 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Comparison of classical diagnostic criteria and Chinese revised diagnostic criteria for fever of unknown origin in Chinese patients

, 2016
Jia-Jun Li, Wen-Xiang Huang, Zheng-Yu Shi, Qiu Sun, Xiao-Juan Xin, Jin-Qiu Zhao, Zhen Yin Department of Infectious Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China Background: Fever of
Xin XJ, Huang WX, Sun Q, Shi ZY, Zhao JQ, Li JJ, Yin Z   +6 more
core  

Diagnostic features of Acanthamoeba keratitis via in vivo confocal microscopy. [PDF]

Sci Rep
Przybek-Skrzypecka J, Armstrong M, Kim J, Walkden A, Au L, Brahma A, Carley F, Chidambaram JD.   +7 more
europepmc   +1 more source