Results 111 to 120 of about 9,889,063 (306)

Diagnostic usefulness of myocardial perfusion imaging in patients reluctant to undergo angiography

, 2016
Akhil Narang, Amita Singh, Amit R Patel Department of Medicine, Section of Cardiology, University of Chicago, Chicago, IL, USA Abstract: Patients with known or suspected coronary artery disease are often referred for ischemic testing to aid in risk ...
Narang A, Singh A, Patel AR
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

‘Do you see what I see?’ Medical imaging: the interpretation of visual information

Röntgen's discovery of x-rays in 1895, gave to medicine the extraordinary benefit of being able to see inside the living body without surgery. Over time, technology has added to the sophistication of imaging processes in medicine and we now have a wide ...
Manning, David J.
core  

Image fusion for dynamic contrast enhanced magnetic resonance imaging

, 2004
Twellmann T, Saalbach A, Gerstung O, Leach MO, Nattkemper TW. Image fusion for dynamic contrast enhanced magnetic resonance imaging. Biomed Eng Online. 2004;3(1): 35.BACKGROUND: Multivariate imaging techniques such as dynamic contrast-enhanced magnetic ...
Nattkemper, Tim Wilhelm ; https://orcid.org/, Nattkemper Tim W, Saalbach, A, Olaf Gerstung, Gerstung, O., Leach, M.O., Twellmann Thorsten, Twellmann, Thorsten, Nattkemper, TW, Axel Saalbach, Tim W Nattkemper, Leach, Martin O, Gerstung Olaf, Twellmann, T Thorsten, Thorsten Twellmann, Gerstung, Olaf, Saalbach Axel, Saalbach, Axel, Leach Martin O, Gerstung, O, Nattkemper, T.W., Martin O Leach, Saalbach, A., Twellmann, T.   +23 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Risk management for chiropractors and Osteopaths: Imaging guidelines for conditions commonly seen in practice

, 2003
This article is the second in a series of articles dealing with risk management in the practise of chiropractic and osteopathy, prepared by the COCA Risk Management Subcommittee.
Pollard, H., Reggars, J.W., Werth, P D, Cameron, M., Werth, P.D., Cameron, M, Vitiello, A, Walker, B.F., French, S D, French, S.D., Vitiello, A., Comrie, D.A., Reggars, J W, Pollard, H, Comrie, D A, Walker, B F   +15 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

The use of QTVR for teaching radiology and diagnostic imaging

, 2001
This paper reports on the preparation of a technology-mediated alternative to print-based external study of a postgraduate unit in veterinary diagnostic imaging.
Richardson, J.L., Phillips, R., Lafitte, F.   +2 more
core