Results 91 to 100 of about 9,889,063 (306)

Contrast enhancement ultrasonography (CEUS) of renal perfusion in dogs with acute kidney injury (AKI)

open access: yes, 2017
Acute kidney injury (AKI) is due to a sudden decrease in renal function. Given the close correlation between the changes in renal microperfusion and renal function, we suggested an ultrasonography study of renal perfusion with CEUS in dogs with AKI ...
Mannucci T, Rota A, Lippi I., Citi S
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Imaging in vitreoretinal diagnostics

open access: yesIndian Journal of Ophthalmology, 2013
Dear Friends, Greetings from the Editor's desk. I am privileged to introduce yet another monthly issue in this diamond jubilee year of our prestigious journal. This edition gives a fruitful insight into a wide range of subjects ranging from intraocular lenses to vein occlusion and retinal diagnostics.
openaire   +3 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Imaging in multiple sclerosis: A new spin on lesions [PDF]

open access: yes, 2016
This article evaluates the most relevant state-of-the-art magnetic resonance (MR) techniques that are clinically available to investigate multiple sclerosis (MS).
Saade, Charbel   +5 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Pattern of Spine Degenerative Disease Among Patients Referred for Lumbar Magnetic Resonance Imaging at Muhimbili National Hospital, Dar es salaam, Tanzania March-September-2010. [PDF]

open access: yes, 2011
Background Degenerative disease of the lumbar spine refers to a syndrome in which an intervertebral disk with adjacent spine structures are compromised. This causes low back and lower extremity pain.
Jacob, Mboka
core  

Small bowel imaging in managing Crohn's Disease patients [PDF]

open access: yes, 2012
The small bowel is essential to sustain alimentation and small bowel Crohn's disease (CD) may severely limit its function. Small bowel imaging is a crucial element in diagnosing small bowel CD, and treatment control with imaging is increasingly used to ...
Albert, Jörg Gerhard, Jörg G. Albert
core   +1 more source

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