Results 101 to 110 of about 3,884,045 (308)

Comparative Analysis of Diagnostic Imaging Modalities for Anatomical Instability in Patellofemoral Pain Disorders: a Systematic Review [PDF]

Patellofemoral pain disorders (PFPD) are characterized by pain around or behind the patella, commonly aggravated by activities such as squatting, running, or stair climbing. Accurate diagnosis of anatomical instability is essential in managing PFPD. This
Lavanya Prathap, Jyothinath Kothapalli, Subhadradevi Velichety, Sandhya Nagolu, Jeyakumar Sankarasubbu   +4 more
core   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Contrast enhancement ultrasonography (CEUS) of renal perfusion in dogs with acute kidney injury (AKI)

, 2017
Acute kidney injury (AKI) is due to a sudden decrease in renal function. Given the close correlation between the changes in renal microperfusion and renal function, we suggested an ultrasonography study of renal perfusion with CEUS in dogs with AKI ...
Mannucci T, Rota A, Lippi I., Citi S
core  

Radiological features of screening-detected and interval breast cancers and subsequent survival in Eastern Finnish women

Scientific Reports
Interval breast cancers are diagnosed between scheduled screenings and differ in many respects from screening-detected cancers. Studies comparing the survival of patients with interval and screening-detected cancers have reported differing results.
Aki Nykänen, Mazen Sudah, Amro Masarwah, Ritva Vanninen, Hidemi Okuma   +4 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Risk management for chiropractors and Osteopaths: Imaging guidelines for conditions commonly seen in practice [PDF]

, 2003
This article is the second in a series of articles dealing with risk management in the practise of chiropractic and osteopathy, prepared by the COCA Risk Management Subcommittee.
Pollard, H., Reggars, J.W., Werth, P D, Cameron, M., Werth, P.D., Cameron, M, Vitiello, A, Walker, B.F., French, S D, French, S.D., Vitiello, A., Comrie, D.A., Reggars, J W, Pollard, H, Comrie, D A, Walker, B F   +15 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Diagnostic usefulness of myocardial perfusion imaging in patients reluctant to undergo angiography [PDF]

, 2016
Akhil Narang, Amita Singh, Amit R Patel Department of Medicine, Section of Cardiology, University of Chicago, Chicago, IL, USA Abstract: Patients with known or suspected coronary artery disease are often referred for ischemic testing to aid in risk ...
Narang A, Singh A, Patel AR
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source