Results 101 to 110 of about 284,617 (309)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Investigating The Problem of Misdiagnosis in Model–Based Fault Diagnosis
International Journal of Applied Mathematics and Computer ScienceThis paper deals with one partly unconscious property of the model-based diagnosis. It discusses occasional contradictions between diagnoses that are logically correct but, in fact, are not consistent with the physical state of the system being diagnosed.
Kóscielny Jan Maciej, Bartyś Michał
doaj +1 more source
Frontiers in PediatricsIn this article, we describe the potential utility and design of chatbots to improve history taking in the pediatric intensive care unit (PICU). The fast-paced, high-stakes environment of the PICU often forces clinicians to obtain only enough information
Candace Collins +4 more
doaj +1 more source
Diagnosis: Reasoning from first principles and experiential knowledge [PDF]
Completeness, efficiency and autonomy are requirements for suture diagnostic reasoning systems. Methods for automating diagnostic reasoning systems include diagnosis from first principles (i.e., reasoning from a thorough description of structure and ...
Lawler, Dennis G., Williams, Linda J. F.
core +1 more source
Inferences of clinical diagnostic reasoning and diagnostic error
Journal of Biomedical Informatics, 2011 This paper discusses clinical diagnostic reasoning in terms of a pattern of If/then/Therefore reasoning driven by data gathering and the inference of abduction, as defined in the present paper, and the inferences of retroduction, deduction, and induction as defined by philosopher Charles Sanders Peirce.
Lawson, Anton E., Daniel, Erno S.
openaire +2 more sources
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
The role of strategy and redundancy in diagnostic reasoning
BMC Medical Education, 2003 Background Diagnostic reasoning is a key competence of physicians. We explored the effects of knowledge, practice and additional clinical information on strategy, redundancy and accuracy of diagnosing a peripheral neurological defect in the hand based on
Feller Sabine +3 more
doaj +1 more source
Qualitative model-based diagnostics for rocket systems [PDF]
A diagnostic software package is currently being developed at NASA LeRC that utilizes qualitative model-based reasoning techniques. These techniques can provide diagnostic information about the operational condition of the modeled rocket engine system or
Fulton, Christopher +3 more
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Diagnostic reasoning techniques for selective monitoring [PDF]
An architecture for using diagnostic reasoning techniques in selective monitoring is presented. Given the sensor readings and a model of the physical system, a number of assertions are generated and expressed as Boolean equations. The resulting system of
Doyle, R. J., Homem-De-mello, L. S.
core +1 more source