Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Outstanding Business Reference Sources: The 2006 Selection of Recent Titles
A selection of business reference sources for ...
BRASS Business Reference Sources Committee
core
Diagnostic Reference Levels for Pediatric CT Examinations Based on Patient Size: A Meta-analysis [PDF]
Background: Patient dose surveys are periodically performed to evaluate whether the patient’s doses are acceptable compared to the recommended and reported diagnostic reference levels (DRLs).
Seyed Salman Zakariaee +2 more
doaj
Determination of Diagnostic Reference Level (DRL) in Common Computed Tomography Examinations with the Modified Quality Control-Based Dose Survey Method in Four University Centers: A Comparison of Methods. [PDF]
Tabesh J +4 more
europepmc +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Outstanding Business Reference Sources: The 2004 Selection of Recent Titles
A selection of business reference sources for ...
BRASS Business Reference Sources Committee
core
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Outstanding Business Reference Sources: The 2010 Selection of Recent Titles
A selection of business reference sources for ...
BRASS Business Reference Sources Committee
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Reference Point Formation Over Time: A Weighting Function Approach [PDF]
Although the concept of reference point dependent preferences has been adopted to almost all fields of behavioral economics, especially marketing and behavioral finance, we still know very little about how decision makers form their reference points ...
Baucells, Manel +2 more
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