Results 121 to 130 of about 14,286,320 (254)

An Analysis of Computed Tomography Diagnostic Reference Levels in India Compared to Other Countries

Diagnostics
Computed Tomography (CT) is vital for diagnosing and monitoring medical conditions. However, increased usage raises concerns about patient radiation exposure. Diagnostic Reference Levels (DRLs) aim to minimize radiation doses in CT imaging.
Maajid Mohi Ud Din Malik, Mansour Alqahtani, Ibrahim Hadadi, Abdullah G. M. AlQhtani, Abdullah Alqarni   +4 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Advanced Computational Methods for Radiation Dose Optimization in CT

Diagnostics
Background: In planning radiotherapy treatments, computed tomography (CT) has become a crucial tool. CT scans involve exposure to ionizing radiation, which can increase the risk of cancer and other adverse health effects in patients.
Shreekripa Rao, Krishna Sharan, Srinidhi Gururajarao Chandraguthi, Rechal Nisha Dsouza, Leena R. David, Sneha Ravichandran, Mubarak Taiwo Mustapha, Dilip Shettigar, Berna Uzun, Rajagopal Kadavigere, Suresh Sukumar, Dilber Uzun Ozsahin   +11 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Patients doses Estimation in Common Diagnostic X-Ray Examinations and Local DRLs Determination for All Types of Patients

Caspian Journal of Health Research, 2016
Objective: Nowadays medical imaging is essential in any medical diagnosis. In 1990, the International commission on radiological protection recommended diagnostic reference level (DRL)  to optimize the X-ray examinations according to the principle of ...
Hossein Rahanjam, Hossein Gharaati, Mohamadreza Kardan, Behzad Fasaee, Arash Akbarzadeh   +4 more
doaj  

An Approach to Establishing Diagnostic Reference Levels in Interventional Pediatric Cardiology from Different Regions of Brazil

Children
Diagnostic reference levels (DRLs) are a pivotal strategy to be implemented since pediatric interventional cardiology procedures are increasing. This work aimed to propose an initial set of Brazilian DRLs for pediatric interventional diagnostic and ...
Viviane K. Asfora, Marcelo B. Freitas, Regina B. Medeiros, Hugo R. Schelin, Akemi Yagui, Marcus V. L. Oliveira, Luiz M. S. A. Leite, Guillermo A. Lopez, Maryanna R. S. Roberto, Fabio L. Gagetti, Pablo H. O. Souza, Bruna Vargas, Valeriy V. Denyak, Helen J. Khoury   +13 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

DEVELOPMENT OF DIAGNOSTIC REFERENCE LEVELS (DRL) OF PATIENTS X-RAY EXPOSURE IN DIAGNOSTIC RADIOLOGY

Радиационная гигиена, 2015
We introduce a system of Diagnostic Reference Levels (DRLs) for patients medical exposure for national health care practice implementation. DRLs are an effective way of the patient radiation protection through the optimization of the medical exposure ...
A. V. Vodovatov, S. A. Kalnitsky, M. I. Balonov, I. G. Kamyshanskaja   +3 more
doaj  

Establishing the Diagnostic Reference Levels for Common Dubai Health Adult Nuclear Medicine Examinations

Life
Nuclear medicine (NM) procedures are performed using unsealed radioactive sources that are administered to patients, resulting in both internal and external exposure for patients and staff alike.
Entesar Z. Dalah, Najlaa K. Al Mazrouei, Zahra A. Al Ali   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source