Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Clinical Indication-Based Pediatric Diagnostic Reference Level Values for Abdominal Computed Tomography: A Descriptive Cross-Sectional Study. [PDF]
Pitso T, Sebelego IK, Muller H.
europepmc +1 more source
Establishment of institutional diagnostic reference level for computed tomography with automated dose-tracking software. [PDF]
Liang CR +5 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Detailed EFSUM recommendations on the scope of ultrasound assessment in patients with portal hypertension considering the diagnostic reference level. [PDF]
Smereczyński A, Kołaczyk K.
europepmc +1 more source
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
The impact of the 2020 diagnostic reference level revision and the development of national regulations on occupational radiation protection in medical facilities in Japan. [PDF]
Tsujiguchi T +8 more
europepmc +1 more source
National diagnostic reference level initiative for computed tomography examinations in Kenya. [PDF]
Korir GK +4 more
europepmc +1 more source
Diagnostic Reference Levels: A Review
openaire +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source

