Results 101 to 110 of about 11,925,434 (289)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Assessing Effective Doses and Proposing DRLs for Pediatric CT Procedures in Madinah (Single Hospital), Saudi Arabia

Applied Sciences
This study aims to assess effective radiation doses (EDs) for pediatric computed tomography (CT) procedures in Madinah (single hospital), Saudi Arabia, and propose diagnostic reference levels (DRLs) for these procedures.
Khalid M. Aloufi, Fahad H. Alhazmi, Faisal A. Alrehily, Nadia S. Alraddadi, Ahmed S. Alharbi, Amjad M. Alamin, Nawaf S. Alraddadi, Abaad A. Alenezi, Fai H. Hadi   +8 more
doaj   +1 more source

Proposal of National Diagnostic Reference Levels for Selected General Radiography Procedures in Ghana [PDF]

Journal of Radiation Protection and Research
Background Diagnostic reference levels (DRLs) are integral to optimizing the patient dose in diagnostic radiology, and yet data for low- and middle-income countries are limited.
Daniel Abbeyquaye, Stephen Inkoom, Shirazu Issahaku, Theresa Bebaaku Dery, David Ebo Anderson, Van Wellington Elloh   +5 more
doaj   +1 more source

Diagnostic reference levels in interventional radiology: a systematic review. [PDF]

Radiol Bras
Abstract Objective: To comprehensively and impartially analyze the scientific evidence available for establishing diagnostic reference levels (DRLs) in interventional radiology. Method: This was a systematic review conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
de Borba IQ, Lykawka R, Soares NM, da Motta Leal Filho JM, Bacelar A, Ruffini ML, de Souza AM, Reis F, Duarte JÁ.   +8 more
europepmc   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Patient dose audit of the most frequent radiographic examinations and the proposed local diagnostic reference levels in southwestern Nigeria: Imperative for dose optimisation

Journal of Radiation Research and Applied Sciences, 2016
Diagnostic reference levels (DRLs) is a veritable tool for dose optimisation and patient protection in diagnostic radiology. However, it is essential to have information on the local situation especially in a large hospital with several units or a ...
N.N. Jibiri, C.J. Olowookere
doaj   +1 more source

Methods of checking the observance of diagnostic reference levels in the field of radiodiagnostics

, 2008
Methods of Checking the Observance of Diagnostic Reference Levels in the Field of Radio diagnostics Although there is a simultaneous development of diagnostic and therapeutic methods, perfection of instrumentation and means for personnel and patient ...
KROUPOVÁ, Helena
core  

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Estimation of Typical Values (DRL) in Angioplasties Performed at a Radiology Service of a Hospital in Southern Brazil

Brazilian Journal of Radiation Sciences
Interventional radiology involves diagnostic and therapeutic interventions using X-ray-emitting equipment. Due to the high radiation doses administered to patients during these procedures, there is a significant risk of severe tissue reactions resulting ...
Fernando Rockembach Mazuim, Isadora Tomanqueves Costa, Florencia Agustina Gutierrez Perez, Cristiny Tretto Lemes Pereira Dutra, Marcos Araquem Scopel, Tiago Trindade Hahn, Catia Simone Griebler Gomes, Daiane Cristini Barbosa Souza   +7 more
doaj   +1 more source