Results 111 to 120 of about 12,449,625 (324)

Optimization and image quality in CT studies: application of DRLs based on clinical indication

Discover Applied Sciences
The use of ionizing radiation in computed tomography (CT) has significantly enhanced diagnostic accuracy and clinical decision-making. However, optimizing CT protocols is crucial to balance the diagnostic benefits with potential radiation risks ...
Carmine Picone, Annamaria Porto, Roberta Fusco, Claudio Granata, Maria Chiara Brunese, Vincenza Granata, Alessandro Ottaiano, Marialuisa Barretta, Ferdinando Caranci, Biagio Pecori, Eugenio Sorgente, Sergio Salerno, Raffaella Mormile, Fabio Pinto, Antonio Pinto, Andrea Magistrelli, Antonella Petrillo   +16 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Diagnostic reference levels for routine computed tomography angiography examinations: a systematic review

The Egyptian Journal of Radiology and Nuclear Medicine
Background This work aims to investigate existing methodologies that have been used to establish diagnostic reference levels (DRLs) for common computed tomography angiography (CTA) examinations in adult patients by analyzing published national and local ...
Ali Bahny Alhailiy
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

DIAGNOSTIC REFERENCE LEVELS FOR CARDIAC CT ANGIOGRAPHY IN AUSTRALIA

Radiation Protection Dosimetry, 2018
This study aims to assess patient radiation dose from cardiac computed tomography angiography (CCTA) with the aim of proposing a national diagnostic reference levels (NDRLs) for CCTA procedures in Australia. A questionnaire was used to retrospectively gather baseline information related to CCTA scanning and patient parameters in CT centres across the ...
Ali B Alhailiy, Ernest U Ekpo, Elaine A Ryan, Peter L Kench, Patrick C Brennan, Mark F McEntee   +5 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The need for national diagnostic reference levels: Entrance surface dose measurement in intraoral radiography [PDF]

, 2004
Background: Intraoral radiographies are the most frequent X-ray examinations in humans. According to International Commission on Radiation Protection (ICRP) recommendations, the selection of a diagnostic reference level (DRL) should be specific to a ...
Shareghi, A., Jafari Zadeh, M., Nazeri, F., Ghiassi-Nejad, M., Mozdarani, Hossein., Mortazavi, M., Kavousi, A   +6 more
core   +1 more source

Diagnostic Reference Levels for Diagnostic and Interventional X-Ray Procedures in Germany: Update and Handling Diagnostische Referenzwerte für diagnostische und interventionelle Röntgenanwendungen in Deutschland: Aktualisierung und Handhabung

RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2019
Purpose Recent developments in medical technology have broadened the spectrum of X-ray procedures and changed exposure practice in X-ray facilities. For this reason, diagnostic reference levels (DRLs) for diagnostic and interventional X-ray procedures ...
A. Schegerer, R. Loose, L. Heuser, G. Brix   +3 more
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Assessing Effective Doses and Proposing DRLs for Pediatric CT Procedures in Madinah (Single Hospital), Saudi Arabia

Applied Sciences
This study aims to assess effective radiation doses (EDs) for pediatric computed tomography (CT) procedures in Madinah (single hospital), Saudi Arabia, and propose diagnostic reference levels (DRLs) for these procedures.
Khalid M. Aloufi, Fahad H. Alhazmi, Faisal A. Alrehily, Nadia S. Alraddadi, Ahmed S. Alharbi, Amjad M. Alamin, Nawaf S. Alraddadi, Abaad A. Alenezi, Fai H. Hadi   +8 more
doaj   +1 more source