Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Applying cognitive diagnostic models to mechanics concept inventories
Physical Review Physics Education ResearchIn physics education research, instructors and researchers often use research-based assessments (RBAs) to assess students’ skills and knowledge. In this paper, we support the development of a mechanics cognitive diagnostic to test and implement effective
Vy Le +7 more
doaj +1 more source
, 2013 Background: Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder affecting motor coordination. Evidence suggests this disorder persists into adulthood and may be associated with biomechanical dysfunction and pain.
Clark, Carol J.
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The Use of Art Observation Interventions to Improve Medical Students' Diagnostic Skills: A Scoping Review. [PDF]
Perspect Med Educ, 2023 Mehta A, Agius S.
europepmc +1 more source
Measuring beginner reading skills: An empirical evaluation of alternative instruments and their potential use for policymaking and accountability in Peru [PDF]
Based on analysis of reading performance data from 475 third-graders in Peru, this study makes recommendations on improving reading tests, choice of reading standards, and how to present the results at the school and individual levels.
Kudo, Ines, Bazan, Jorge
core
A consideration of diagnostic reasoning skills in nurse practitioners-measures and influences [PDF]
, 2022 This study considered the diagnostic reasoning skills employed by nurse practitioners and nurse practitioner students and factors that may influence the diagnostic reasoning process.
King, Pamela L.
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
How can the postgraduate training program in pathology departments in India be improved?
Indian Journal of Pathology and Microbiology, 2011 There exists a wide variation in the competence of the postgraduate residents trained in pathology in different institutions across India. This results in strong disparities in the clinical diagnostic skills, teaching skills, research capabilities and ...
Shivayogi R Bhusnurmath +1 more
doaj +1 more source
Stroke of Genius: A Customizable Card Game Structure to Exercise Differential Diagnostic Skills. [PDF]
J Grad Med Educ, 2023 Helms A, Friedland DR, Dhyani R.
europepmc +1 more source