Results 101 to 110 of about 4,878,939 (297)
The issue of accounting fraud presents a significant challenge within the business sector, prompting an increase in scholarly investigations across various contexts.
Narinthon Imjai +4 more
doaj +1 more source
Assessing Resident Diagnostic Skills Using a Modified Bronchiolitis Score. [PDF]
Rivera-Sepulveda A, Isona M.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Developmental coordination disorder (DCD) is a neurodevelopmental disorder which affects different areas of an individual's everyday living and learning.
Tjasa Filipcic, Jerneja Tercon
doaj +2 more sources
Michael P Boniface,1 Scott A Helgeson,2 Jed C Cowdell,2 Leslie V Simon,1 Brett T Hiroto,2 Monia E Werlang,2 Sarah W Robison,2 Grace G Edwards,3,4 Michele D Lewis,2 Michael J Maniaci2 1Department of Emergency Medicine, Mayo Clinic, Jacksonville, FL, USA ...
Boniface MP +9 more
doaj
Skills not roles: the key to better training and better patient care
Introduction: The NHS faces unprecedented challenges in delivering efficient, effective and safe patient care; practical procedure skills are an essential component of this.
Eve Rushforth, Burhan Khan
doaj +1 more source
The effect of a dermato-oncological training programme on the diagnostic skills and quality of referrals for suspicious skin lesions by general practitioners. [PDF]
Marra E +7 more
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

