Results 71 to 80 of about 16,288,597 (342)
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Meta-analysis of diagnostic test accuracy studies differs from the usual meta-analysis of therapeutic/interventional studies in that, it is required to simultaneously analyze a pair of two outcome measures such as sensitivity and specificity, instead of ...
Juneyoung Lee+4 more
semanticscholar +1 more source
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source
Development of Multiplexed Infectious Disease Lateral Flow Assays: Challenges and Opportunities
Lateral flow assays (LFAs) are the mainstay of rapid point-of-care diagnostics, with the potential to enable early case management and transform the epidemiology of infectious disease. However, most LFAs only detect single biomarkers.
Khayriyyah Mohd Hanafiah+5 more
doaj +1 more source
Acute SARS-CoV-2 infection has been associated with false-positive HIV screening tests. The underlying mechanism is unclear, and for clinical cases, evidence beyond a temporal connection is missing. However, several experimental studies point toward SARS-
Carina Elsner+8 more
doaj +1 more source
Clinical medicine is an important part of scientific medicine that is all too often neglected when treating rodents and small mammal pets. As with more traditional pets, a progressive diagnostic regimen should include a thorough history, clinical signs, physical examination, and laboratory findings.
openaire +2 more sources
A combined treponemal and nontreponemal rapid diagnostic test was found to have good sensitivity and specificity for both syphilis and yaws. The performance of both the treponemal and nontreponemal test components was strongly associated with the rapid ...
M. Marks+17 more
semanticscholar +1 more source
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen+13 more
wiley +1 more source
Objective (s): Acute appendicitis happens in 7% of people during their lives, but there is no consensus about criteria for emergency appendectomy. TI1is study was carried out to determine the appropriate combination of diagnostic tests and variables ...
Borhani M.+4 more
doaj
Development of A Four-Tier Diagnostic Test For Misconception of Oscillation and Waves
Difficulty understanding students' concepts needs to be known so that improvements can be made so that eventually students can master the concepts well. Misconception diagnostic tests can be an alternative to uncovering causes or factors of misconception
Ridho Adi Negoro, Viga Karina
doaj +1 more source