Results 71 to 80 of about 16,288,597 (342)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Systematic Review and Meta-Analysis of Studies Evaluating Diagnostic Test Accuracy: A Practical Review for Clinical Researchers-Part II. Statistical Methods of Meta-Analysis

Korean Journal of Radiology, 2015
Meta-analysis of diagnostic test accuracy studies differs from the usual meta-analysis of therapeutic/interventional studies in that, it is required to simultaneously analyze a pair of two outcome measures such as sensitivity and specificity, instead of ...
Juneyoung Lee, K. Kim, S. Choi, Jimi Huh, S. Park   +4 more
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Development of Multiplexed Infectious Disease Lateral Flow Assays: Challenges and Opportunities

Diagnostics, 2017
Lateral flow assays (LFAs) are the mainstay of rapid point-of-care diagnostics, with the potential to enable early case management and transform the epidemiology of infectious disease. However, most LFAs only detect single biomarkers.
Khayriyyah Mohd Hanafiah, Norsyahida Arifin, Yazmin Bustami, Rahmah Noordin, Mary Garcia, David Anderson   +5 more
doaj   +1 more source

False-Positive Screening and Confirmatory HIV Diagnostic Test in a Patient with Cured SARS-CoV-2 Infection Is Not Mediated by Env/Spike Cross-Reactive Antibodies

Viruses, 2023
Acute SARS-CoV-2 infection has been associated with false-positive HIV screening tests. The underlying mechanism is unclear, and for clinical cases, evidence beyond a temporal connection is missing. However, several experimental studies point toward SARS-
Carina Elsner, Gwenllian A. Appeltrath, Margarethe Konik, Janine Parreuter, Martina Broecker-Preuss, Adalbert Krawczyk, Stefan Esser, Stefanie Sammet, Christina B. Karsten   +8 more
doaj   +1 more source

Rodent Diagnostic Testing

Journal of Exotic Pet Medicine, 2008
Clinical medicine is an important part of scientific medicine that is all too often neglected when treating rodents and small mammal pets. As with more traditional pets, a progressive diagnostic regimen should include a thorough history, clinical signs, physical examination, and laboratory findings.
openaire   +2 more sources

Metaanalysis of the Performance of a Combined Treponemal and Nontreponemal Rapid Diagnostic Test for Syphilis and Yaws

Clinical Infectious Diseases, 2016
A combined treponemal and nontreponemal rapid diagnostic test was found to have good sensitivity and specificity for both syphilis and yaws. The performance of both the treponemal and nontreponemal test components was strongly associated with the rapid ...
M. Marks, Yueping Yin, Xiangsheng Chen, Arnold Castro, L. Causer, R. Guy, R. Wangnapi, O. Mitjà, A. Aziz, R. Castro, F. da Luz Martins Pereira, F. Taleo, J. Guinard, L. Bélec, Y. Tun, C. Bottomley, R. Ballard, D. Mabey   +17 more
semanticscholar   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Assessment of the accuracy of diagnostic tests in patients with suspected acute appendicitis using ROC analysis

Payesh, 2006
Objective (s):  Acute appendicitis happens in 7% of people during their lives, but there is no consensus about criteria for emergency appendectomy. TI1is study was carried out to determine the appropriate combination of diagnostic tests and variables ...
Borhani M., Mohammad K., Holakoie K., Majdzadeh S.R., Kaviani A.   +4 more
doaj  

Development of A Four-Tier Diagnostic Test For Misconception of Oscillation and Waves

JPPPF: Jurnal Penelitian & Pengembangan Pendidikan Fisika, 2019
Difficulty understanding students' concepts needs to be known so that improvements can be made so that eventually students can master the concepts well. Misconception diagnostic tests can be an alternative to uncovering causes or factors of misconception
Ridho Adi Negoro, Viga Karina
doaj   +1 more source