Results 81 to 90 of about 1,631,567 (280)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Application of Local Influence Diagnostics to the Linear Logistic Regression Models [PDF]

open access: yes
This paper focuses the development of the diagnostics for the perturbations of case-weights and explanatory variables (one or more) in a linear logistic regression model.
M. ATAHARUL ISLAM, MONZUR HOSSAIN
core  

UV, optical and near-IR diagnostics of massive stars [PDF]

open access: yes, 2010
We present an overview of a few spectroscopic diagnostics of massive stars. We explore the following wavelength ranges: UV (1000 to 2000 A), optical (4000--7000 A) and near-infrared (mainly H and K bands).
Martins, F.
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Climate diagnostics [PDF]

open access: yes
Diagnoses of climate fluctuations is examined emphasizing the assemblage of a host of observations, to develop a clearer physical picture of the nature and causal interrelationships of the climate events.

core   +1 more source

Statistical Uncertainties in Temperature Diagnostics for Hot Coronal Plasma Using the ASCA SIS

open access: yes, 1994
Statistical uncertainties in determining the temperatures of hot (0.5 keV to 10 keV) coronal plasmas are investigated. The statistical precision of various spectral temperature diagnostics is established by analyzing synthetic ASCA Solid-state Imaging ...
O'Dell, S. L.   +3 more
core   +1 more source

Development and analytical performance of a new research use only (RUO) GP73 automated immunoassay

open access: yesBiochemistry and Biophysics Reports
Golgi protein 73 (GP73) is a serum marker with potential applications in the assessment of chronic liver disease progression. We developed a research use only (RUO) GP73 immunoassay to detect serum GP73 concentration.
Shaohua Ning   +13 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Developement of real time diagnostics and feedback algorithms for JET in view of the next step

open access: yes, 2004
Real time control of many plasma parameters will be an essential aspect in the development of reliable high performance operation of Next Step Tokamaks.
A Murari   +32 more
core   +2 more sources

Extracellular vesicles from plasma have higher tumour RNA fraction than platelets

open access: yesJournal of Extracellular Vesicles, 2020
In addition to Circulating Tumour Cells (CTCs), cell-free DNA (cfDNA) and Extracellular Vesicles (EVs), the notion of “Tumour-Educated Platelets” (TEP) has recently emerged as a potential source of tumour-derived biomarkers accessible through blood ...
Kay Brinkman   +6 more
doaj   +1 more source

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