Results 71 to 80 of about 1,116,177 (240)
General Outdoor Air Economizer Fault Detection & Diagnostics Assessment Method [PDF]
, 2012 Outdoor air economizers (OAE) control the amount of air drawn into a building in order to reduce energy usage and improve indoor air quality. Air-side economizers are required by energy standards such as ASHRAE Standard 90.1 in many commercial ...
Hjortland, Andrew L., Braun, James E.
core +1 more source
Nanopore based RNA methylation profiling of a circulating lung cancer biomarker
Communications MedicineBackground The characterisation of circulating nucleic acid biomarkers in liquid biopsy based diagnostics holds great potential to transform the landscape of early cancer detection and screening.
Marta Sanchez-Delgado +17 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A DNA alteration and methylation co-detection method for clinical purpose
EMBO Molecular MedicineTraditional approaches for capturing genomic alterations and DNA methylation require separate assays, complicating clinical workflows and limiting sample utilization, particularly with low-input materials like cell-free DNA.
Jiyan Yu +12 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
BMC Medical Genomics, 2018 Background There is a clear need for assays that can predict the risk of metastatic prostate cancer following curative procedures. Importantly these assays must be analytically robust in order to provide quality data for important clinical decisions. DNA
Paul Wallace Medlow +17 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Plasma Diagnostics and Atomic Processes
, 1990 Spectroscopic plasma diagnostics with the use of atomic processes are discussed relating to three subjects in the followings. i) Time resolved X-ray spectra of titanium helium-like ions from tokamaks.
"Kato, T."
core