Results 61 to 70 of about 287,081 (299)
CRISPR-Cas-Based Diagnostics in Biomedicine: Principles, Applications, and Future Trajectories
BiosensorsCRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas (CRISPR-associated) systems, originally identified as prokaryotic adaptive immune mechanisms, have rapidly evolved into powerful tools for molecular diagnostics.
Zhongwu Zhou +2 more
doaj +1 more source
A Fiber Optic Probe for the Detection of Cataracts [PDF]
, 1993 A compact fiber optic probe developed for on-orbit science experiments was used to detect the onset of cataracts, a capability that could eliminate physicians' guesswork and result in new drugs to 'dissolve' or slow down the cataract formation before ...
Ansari, Rafat R., Dhadwal, Harbans S.
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Bipolar II disorder: principles of diagnostics and therapy
RUDN Journal of Medicine, 2013 The article deals with the results of study of patients with diagnosed recurrent depressive disorder. The diagnostic criteria, clinical manifestations, psychological and social aspects and possibilities of therapy of bipolar II disorder are discussed.
R G Akzhyguitov, V L Karnozov
doaj
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Review—Quantum Biosensors: Principles and Applications in Medical Diagnostics
ECS Sensors PlusOriginating at the intersection of physics and biosensing, quantum biosensors (QB) are transforming medical diagnostics and personalized medicine by exploiting quantum phenomena to amplify sensitivity, specificity, and detection speed compared to ...
Suparna Das +4 more
doaj +1 more source
Choosing Wavelet Methods, Filters, and Lengths for Functional Brain Network Construction
, 2015 Wavelet methods are widely used to decompose fMRI, EEG, or MEG signals into time series representing neurophysiological activity in fixed frequency bands.
Bassett, Danielle S. +4 more
core +3 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Results for the response function determination of the Compact Neutron Spectrometer
, 2012 The Compact Neutron Spectrometer (CNS) is a Joint European Torus (JET) Enhancement Project, designed for fusion diagnostics in different plasma scenarios. The CNS is based on a liquid scintillator (BC501A) which allows good discrimination between neutron
+16 more
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source