Results 1 to 10 of about 640,319 (303)

Hepatoprotective effects of silymarin in management of liver injury caused by tuberculosis treatment

Drugs in Context, 2023
Tuberculosis (TB) is a chronic infection of global-health concern because of its high incidence, costly medical treatment, drug resistance and risk of co-infections. Anti-TB treatment involves a combination of drugs with high degree of liver toxicity,
Yeong Yeh Lee, Vincent Tee
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The Nrf2 Pathway in Liver Diseases

Frontiers in Cell and Developmental Biology, 2022
Oxidative stress is the leading cause of most liver diseases, such as drug-induced liver injury, viral hepatitis, and alcoholic hepatitis caused by drugs, viruses, and ethanol.
Jiaming Zhou, Qiuxian Zheng, Zhi Chen
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United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts

Toxicology Reports, 2020
As part of the United States Pharmacopeia’s ongoing review of dietary supplement safety data, a new comprehensive systematic review on green tea extracts (GTE) has been completed.
Hellen A. Oketch-Rabah, Amy L. Roe, Cynthia V. Rider, Herbert L. Bonkovsky, Gabriel I. Giancaspro, Victor Navarro, Mary F. Paine, Joseph M. Betz, Robin J. Marles, Steven Casper, Bill Gurley, Scott A. Jordan, Kan He, Mahendra P. Kapoor, Theertham P. Rao, Averell H. Sherker, Robert J. Fontana, Simona Rossi, Raj Vuppalanchi, Leonard B. Seeff, Andrew Stolz, Jawad Ahmad, Christopher Koh, Jose Serrano, Tieraona Low Dog, Richard Ko   +25 more
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Microtechnology-based in vitro models: Mimicking liver function and pathophysiology

APL Bioengineering, 2021
The liver plays important roles in drug metabolism and homeostasis. The metabolism and biotransformation can not only affect the efficacy of drugs but also result in hepatotoxicity and drug-induced liver injury.
Seung Yeon Lee, Donghyun Kim, Seung Hwan Lee, Jong Hwan Sung   +3 more
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Features of indicators of the functional state of the liver, immune link, cytokine regulation and carbohydrate metabolism in patients with toxic chronic diffuse liver diseases

Gastroenterologìa, 2020
Background. The problem of the development and progression of chronic diffuse liver diseases is currently one of the most important in modern gastroenterology, it has general medical and social significance.
V.I. Didenko, О.M. Tatarchuk, S.L. Melanich, O.P. Petishko   +3 more
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Natural Products for Acetaminophen-Induced Acute Liver Injury: A Review

Molecules, 2023
The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to damage from various factors such as viral infections, drug reactions, excessive alcohol consumption, and autoimmune diseases.
Xiaoyangzi Li, Ruyang Lao, Jiawei Lei, Yuting Chen, Qi Zhou, Ting Wang, Yingpeng Tong   +6 more
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Deciphering the liver enigma: distinguishing drug-induced liver injury and metabolic dysfunction-associated steatotic liver disease—a comprehensive narrative review

Exploration of Digestive Diseases, 2023
Drug-induced liver injury (DILI) poses a complex and heterogeneous clinical challenge, which often resembles non-drug related acute or chronic liver diseases, such as metabolic dysfunction-associated steatotic liver disease (MASLD).
Miren García-Cortés, Juan Pedro Toro-Ortiz, Alberto García-García   +2 more
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Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis

JHEP Reports, 2020
Background & Aims: Liver diseases are caused by many factors, such as genetics, nutrition, and viruses. Therefore, it is important to delineate transcriptomic changes that occur in various liver diseases.
Bhoomika Mathur, Waqar Arif, Megan E. Patton, Rahiman Faiyaz, Jian Liu, Jennifer Yeh, Sanjiv Harpavat, Kristina Schoonjans, Auinash Kalsotra, Antony M. Wheatley, Sayeepriyadarshini Anakk   +10 more
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An Integrative Pharmacology Based Analysis of Refined Liuweiwuling Against Liver Injury: A Novel Component Combination and Hepaprotective Mechanism

Frontiers in Pharmacology, 2021
Liver disease is a major cause of illness and death worldwide. In China, liver diseases, primarily alcoholic and nonalcoholic fatty liver disease, and viral hepatitis, affect approximately 300 million people, resulting in a major impact on the global ...
Yuan Gao, Wei Shi, Wei Shi, Hongyu Yao, Yongqiang Ai, Yongqiang Ai, Ruisheng Li, Zhilei Wang, Zhilei Wang, Tingting Liu, Tingting Liu, Wenzhang Dai, Wenzhang Dai, Xiaohe Xiao, Xiaohe Xiao, Jun Zhao, Ming Niu, Zhaofang Bai, Zhaofang Bai   +18 more
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Liver involvement in rheumatic diseases

Rheumatology, 2020
Liver involvement in rheumatic diseases may occur as a primary liver disease, primary rheumatic disease with hepatic manifestations or antirheumatic drug-induced liver disease.
Joanna Podgórska, Paulina Werel, Jakub Klapaczyński, Dorota Orzechowska, Mariusz Wudarski, Andrzej Gietka   +5 more
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