Results 71 to 80 of about 287,081 (299)

REQUIREMENTS ON THE DESIGN OF THE AUTOMATED SYSTEM OF PEDAGOGICAL DIAGNOSTICS

open access: yesІнформаційні технології і засоби навчання, 2011
Problem of the design of the pedagogical diagnostics system, which provides the educational system with a feedback, become actual, when information technologies are used in educational process.
Oleksandr H. Kolhatin
doaj  

A Review of Design Principles for Community-based Natural Resource Management

open access: yesEcology and Society, 2010
In 1990, Elinor Ostrom proposed eight design principles, positing them to characterize robust institutions for managing common-pool resources such as forests or fisheries.
Michael Cox   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Perspectives and principles of formulation of legal basis of diagnostic quality control of materials and products of nanostructure composites

open access: yesMATEC Web of Conferences, 2017
In the paper we discuss the problems of perspective of formulation of legal basis of diagnostics quality control of materials and products of nanostructured composites for various application, including the perspective markets of the National Technology ...
Baryshev Gennady K.   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Paroxysmal supraventricular tachycardias: modern principles of diagnostics and treatment

open access: yesКардиоваскулярная терапия и профилактика, 2005
The article is devoted to one of the most actual problems in modern arrhythmology - treatment of paroxysmal supraventricular tachycardias. Modern views on diagnostics and treatment of atrio-ventricular (AV) nodal reciprocating tachycardia and AV ...
A. V. Vetluzhsky, I. G. Fomina
doaj  

Chronic pancreatitis: exocrine insufficiency and its correction

open access: yesЛечащий Врач, 2021
The article represents modern views on methods of diagnostics and treatment of chronic pancreatitis (CP). Principles of replacement enzyme therapy of pancreas exocrine insufficiency were considered.
T. E. Polunina
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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