Results 41 to 50 of about 25,608 (296)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Adaptive processing with signal contaminated training samples [PDF]

open access: yes, 2013
We consider the adaptive beamforming or adaptive detection problem in the case of signal contaminated training samples, i.e., when the latter may contain a signal-like component.
Bidon, Stéphanie   +3 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Knowledge-aided STAP in heterogeneous clutter using a hierarchical bayesian algorithm [PDF]

open access: yes, 2011
This paper addresses the problem of estimating the covariance matrix of a primary vector from heterogeneous samples and some prior knowledge, under the framework of knowledge-aided space-time adaptive processing (KA-STAP).
Bidon, Stéphanie   +5 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Shear strengthening of wall panels through jacketing with cement mortar reinforced by GFRP grids

open access: yes, 2014
This paper gives the results of a series of shear tests carried out on historic wall panels reinforced with an innovative technique by means of jacketing with GFRP (Glass Fiber Reinforced Plastics) mesh inserted into an inorganic matrix.
Borri A.   +7 more
core   +1 more source

Characterization of sheet formability limits using a novel diagonal-cruciform test specimen

open access: yesAdvances in Industrial and Manufacturing Engineering
This paper introduces an innovative diagonal-cruciform test specimen that significantly enhances the characterization of formability limits in sheet metal forming.
Rui F.V. Sampaio   +6 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Quasi-static cyclic tests of two U-shaped RC walls under diagonal loading

open access: yes, 2016
Reinforced concrete core walls are often used to provide horizontal stiffness and strength to mid- or high-rise buildings. The design practice is, however, largely based on findings from tests and analysis of rectangular walls subjected to uni ...
Raluca Constantin (2900756)   +1 more
core   +1 more source

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