Results 61 to 70 of about 148,969 (298)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Approach of wideband robust adaptive beamforming based on microphone arrays

open access: yesTongxin xuebao, 2006
The approach of wideband robust adaptive beamforming (RABF) for speech enhancement based on micro-phone arrays was investigated. It combined the technologies of frequency focusing and diagonal loading, with the former aiming at frequency domain ...
LIN Jing-ran   +3 more
doaj   +2 more sources

Robust Adaptive Beamforming against Signal Steering Vector Mismatch and Jammer Motion

open access: yesInternational Journal of Antennas and Propagation, 2015
Since adaptive beamformer suffers from output performance degradation in the presence of interference nonstationarity and signal steering vector mismatch, a novel robust null broadening adaptive beamforming is proposed. The proposed method is realized by
Xiaojun Mao   +4 more
doaj   +1 more source

MHD consistent cellular automata (CA) models II. Applications to solar flares

open access: yes, 2000
In Isliker et al. (2000b), an extended cellular automaton (X-CA) model for solar flares was introduced. In this model, the interpretation of the model's grid-variable is specified, and the magnetic field, the current, and an approximation to the electric
A. Anastasiadis   +28 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Robust adaptive beamforming algorithm

open access: yesTongxin xuebao, 2009
The performance of least mean squares(LMS) algorithm degraded dramatically in the presence of even slight steering vector mismatches.In order to overcome the shortage,a novel robust adaptive beamforming algorithm based on the variable diagonal loading ...
SONG Xin   +3 more
doaj   +2 more sources

Robust Recursive Algorithm under Uncertainties via Worst-Case SINR Maximization

open access: yesJournal of Electrical and Computer Engineering, 2015
The performance of traditional constrained-LMS (CLMS) algorithm is known to degrade seriously in the presence of small training data size and mismatches between the assumed array response and the true array response.
Xin Song   +3 more
doaj   +1 more source

Generalized Triangular Decomposition in Transform Coding [PDF]

open access: yes, 2010
A general family of optimal transform coders (TCs) is introduced here based on the generalized triangular decomposition (GTD) developed by Jiang This family includes the Karhunen-Loeve transform (KLT) and the generalized version of the prediction-based ...
Chen, Chun-Yang   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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