Results 81 to 90 of about 808,226 (293)
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Experimental Study of Pre-Tensioned Polygonal Prestressed T-Beam Under Combined Loading Condition
BuildingsIn order to investigate the mechanical behavior of a novel pre-tensioned polygonal prestressed T-beam subject to combined bending, shear, and torsion, this study meticulously designed and fabricated a full-scale specimen with a calculated span of 28.28 m,
Zengbo Yao +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Trois questions à Michel Fournier, président de l'association des maires ruraux de France
Michel Fournier est une figure de la ruralité dans les Vosges et au niveau national depuis son élection comme président de l’AMRF en 2020. Impliqué de près dans toutes les dynamiques en faveur du monde rural dans son département comme à l’ANCT dont il ...
Revue d'urbanisme Diagonal
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
A Novel Robust Adaptive Beamformer using Diagonal Loading
International Journal of Computer Applications, 2011 beamfomer which utilizes MVDR beamformer along with SMI (sample matrix inversion), actual data is not available to calculate the covariance matrix. Instead, covariance matrix is estimated from the available data. It may result in bad conditioning.
R. Sukanesh, T.S.Jeyali Laseetha
openaire +1 more source
N° 207 : Le logement, des maux et des remèdes
, 2019 Sommaire Diagonal N°207 Dans une société qui à certains égards se fragilise et se complexifie, la question sociale du logement se pose avec d’autant plus d’acuité. L’explosion des prix et des loyers dans les grandes métropoles, la difficulté d’accès à un
Revue Diagonal
core
L’appel à projets “Des solutions fondées sur la nature pour adapter les territoires côtiers à l’érosion” vient d’être lancé par le ministère de la Transition écologique et de la cohésion des territoires.
Revue d'urbanisme Diagonal
core +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source