Results 91 to 100 of about 1,765,796 (262)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

ANALYSIS AND SIMULATION OF REFRIGERATION UNIT OPERATION ON THE REFRIGERATOR-2 BENCH SIMULATOR

open access: yesШәкәрім университетінің хабаршысы: Техника ғылымдар
In this work, detailed experimental studies were carried out aimed at testing the operating modes of the refrigeration unit "Refrigerator-2" model STX 02.00.01.
D. Nurgaliyev   +4 more
doaj   +1 more source

Normatividad entre esteticidad y tecnicidad según Simondon: hacia una Estética del Derecho como Mecanología de las normas jurídicas

open access: yesARS, 2019
RESUMEN En el presente trabajo proponemos un abordaje del fenómeno de la normatividad al que llamamos Estética del Derecho. Nos basamos, para ello, en la propuesta de una Mecanología utilizada por Gilbert Simondon para abordar el fenómeno de la ...
Gonzalo S. Aguirre
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Building Bridges in Cardio-Oncology: The Role of Clinics in Multidisciplinary Care and Patient Outcomes

open access: yesIndonesian Journal of Cancer
Cardio-oncology is a specialized field within cardiology that focuses on the relationship between cancer, its therapies, and cardiovascular health. This multidisciplinary domain, involving cardiology, hematology, and oncology, addresses the significant ...
Sidhi Laksono
doaj   +1 more source

From theater to laboratory: two regimes of apparatus in the material assemblages of media culture

open access: yesJournal of Aesthetics & Culture, 2019
This research examines the apparatus concepts in the last decades of film studies, from the apparatus theory in the 1970s to the revisionist historiography of the early cinema and new media theory after the 1980s.
Sungyong Ahn
doaj   +1 more source

Answering a question with Deleuze: How is it possible to think with painting? [PDF]

open access: yesحکمت و فلسفه
It is commonly believed that thinking is only for philosophical discourse and philosophers. The main question of the research is as follows: How and in what way does thinking “with” painting take place?
Farideh Afarin
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Results of exploring the force impact of 25 tf open-box cars on the rails of curved tracks

open access: yesВестник Научно-исследовательского института железнодорожного транспорта
Introduction. Onboarding rolling stock that exerts increased axial loads makes assessing wheels force impact on railway tracks more acute and relevant.
A. Yu. Lugovsky, O. K. Bogdanov
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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