Results 61 to 70 of about 3,965,801 (321)

Synchronization of Kuramoto Oscillators on Knots

open access: yes, 2013
A knot is a circle embedded in the space. Projecting a knot on a plane, we obtain a diagram which is known as the knot diagram. The vertices of the diagram, where the curved lines are crossed, can be considered as sites occupied by oscillators.
Sparavigna, Amelia Carolina
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

The Granular Phase Diagram

open access: yes, 1996
The kinetic energy distribution function satisfying the Boltzmann equation is studied analytically and numerically for a system of inelastic hard spheres in the case of binary collisions.
A. Isihara   +14 more
core   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

The semiotics of models

open access: yesSign Systems Studies, 2018
The paper sheds light on the concept of model in ordinary language and in scientific discourse from the perspective of C. S. Peirce’s semiotics. It proposes a general Peircean framework for the definition of models of all kinds, including mental models ...
Winfried Nöth
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

From theater to laboratory: two regimes of apparatus in the material assemblages of media culture

open access: yesJournal of Aesthetics & Culture, 2019
This research examines the apparatus concepts in the last decades of film studies, from the apparatus theory in the 1970s to the revisionist historiography of the early cinema and new media theory after the 1980s.
Sungyong Ahn
doaj   +1 more source

Normatividad entre esteticidad y tecnicidad según Simondon: hacia una Estética del Derecho como Mecanología de las normas jurídicas

open access: yesARS, 2019
RESUMEN En el presente trabajo proponemos un abordaje del fenómeno de la normatividad al que llamamos Estética del Derecho. Nos basamos, para ello, en la propuesta de una Mecanología utilizada por Gilbert Simondon para abordar el fenómeno de la ...
Gonzalo S. Aguirre
doaj   +1 more source

Analysis of the Energy Balance of Friction on the Rolling Contact

open access: yesTribology in Industry, 2021
The state of elastic rolling of the wheel is considered as a special manifestation of the highly developed evolution of the plastic contact of rolling friction.
S.V. Fedorov
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

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