Results 81 to 90 of about 4,142,479 (322)

From theater to laboratory: two regimes of apparatus in the material assemblages of media culture

open access: yesJournal of Aesthetics & Culture, 2019
This research examines the apparatus concepts in the last decades of film studies, from the apparatus theory in the 1970s to the revisionist historiography of the early cinema and new media theory after the 1980s.
Sungyong Ahn
doaj   +1 more source

Multistability in an unusual phase diagram induced by the competition between antiferromagnetic-like short-range and ferromagnetic-like long-range interactions

open access: yes, 2018
The interplay between competing short-range (SR) and long-range (LR) interactions can cause nontrivial structures in phase diagrams. Recently, horn-shaped unusual structures were found by Monte Carlo simulations in the phase diagram of the Ising ...
Miyashita, Seiji   +3 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Answering a question with Deleuze: How is it possible to think with painting? [PDF]

open access: yesحکمت و فلسفه
It is commonly believed that thinking is only for philosophical discourse and philosophers. The main question of the research is as follows: How and in what way does thinking “with” painting take place?
Farideh Afarin
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Transforming timing diagrams into knowledge acquisition in automated specification

open access: yes, 2007
Requirements engineering is an important part of developing programs. It is an essential stage of the software development process that defines what a product or system should to achieve.
Joochim, Tossaporn, Poppleton, Mike
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

An Unknotting Index for Virtual Links

open access: yes, 2018
Given a virtual link diagram $D$, we define its unknotting index $U(D)$ to be minimum among $(m, n)$ tuples, where $m$ stands for the number of crossings virtualized and $n$ stands for the number of classical crossing changes, to obtain a trivial link ...
Kaur, Kirandeep   +2 more
core  

A V-Diagram for the Design of Integrated Health Management for Unmanned Aerial Systems [PDF]

open access: yes, 2015
Designing Integrated Vehicle Health Management (IVHM) for Unmanned Aerial Systems (UAS) is inherently complex. UAS are a system of systems (SoS) and IVHM is a product-service, thus the designer has to take into account many factors, such as: the design ...
BAE Systems   +5 more
core  

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