Results 161 to 170 of about 488,885 (309)

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

POS-350 REASONS FOR FIRST NEPHROLOGY CONSULTATION IN THE ELDERLY

Kidney International Reports, 2021
Y. ELOUAER, D. Zellama, S. Mrabet, M.R. Troudi, A. Fradi, S. Amor, N. Ben Aicha, F. Sabri, A. Azzabi, W. Sahtout, Y. Guedri, A. Achour   +11 more
doaj   +1 more source

Type of dialysis may influence the prognostic value of myocardial perfusion imaging in end stage renal disease: an observational [¹³N]NH₃ PET/CT study. [PDF]

EJNMMI Res
Wenning C, Gosmann TM, Vrachimis A, Schäfers MA, Reuter S.   +4 more
europepmc   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

POS-782 INFECTIOUS COMPLICATIONS IN KIDNEY TRANSPLANTATION

Kidney International Reports, 2021
Y. ELOUAER, N. Ben Aicha, A. Azzabi, W. Sahtout, S. Agrebi, M.R. Troudi, S. Mrabet, A. Fradi, Y. Guedri, D. Zellama, A. Abdellatif   +10 more
doaj   +1 more source

Experiences of moderate-to-severe demoralization syndrome among patients receiving maintenance hemodialysis: a qualitative study. [PDF]

Front Psychol
Bao J, Yin Y, Cheng X, Jiang X, Luo B, Guo S, Xu J, Qian M.   +7 more
europepmc   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

Exploring the suboptimal use of home-based kidney replacement therapies through the lens of structural injustice. [PDF]

Clin Kidney J
Van Biesen W, Sterckx S, Clause AL, Davies S.   +3 more
europepmc   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Comparison of Serum Calcium, Phosphorus, Alkaline Phosphatase, and Intact Parathyroid Hormone Levels Between Dialysis-Dependent and Non-Dialysis-Dependent Patients With Chronic Kidney Disease: A Cross-Sectional Observational Study. [PDF]

Cureus
Ahmad M, Gupta AC, Gulati Y, Gond JK, Qamar M.   +4 more
europepmc   +1 more source