Results 181 to 190 of about 347,613 (269)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Uromodulin and Tryptophan Metabolite Clearance in Hemodialyzed Patients. [PDF]

J Clin Med
Zakrocka I, Kozioł M, Więckowska-Deroń M, Boczkowska S, Kloc R, Kocki T, Olender A, Urbańska EM, Załuska W, Kronbichler A.   +9 more
europepmc   +1 more source

Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors

Advanced Science, EarlyView.
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang, Qian Cheng, Ziyi Wang, Jianwen Wei, Qun Guan, Huazhong Yu, Qingwen Zhang, Caixia Yin, Ruibing Wang   +8 more
wiley   +1 more source

WCN24-1790 HEMOLYTIC UREMIC SYNDROME SECONDARY TO URINARY INFECTION DUE TO ESCHERICHIA COLI: DOES IT EXIST? CASE REPORT

Kidney International Reports
Ivanna Gardarian, Vanesa Fauda, Ana Saez, Nadia Ortiz, Claudia Yeneris, Luz Bendersky, Rocio Busolo, Cenith Contrera, Natalia Salazar, Juan Ibañez, Marta Adragna   +10 more
doaj   +1 more source

Translation, cross-cultural adaptation and psychometric validation of the Brazilian version of the dialysis patient-perceived exercise benefits and barriers scale. [PDF]

J Bras Nefrol
Silva GAD, Gomes CAFP, Stella TC, Miura BG, Zheng J, Foresto RD, Palma RK, Dibai-Filho AV, Sampaio LMM.   +8 more
europepmc   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Predicting intradialytic exercise intolerance in maintenance hemodialysis patients: an interpretable machine learning approach integrating functional assessments. [PDF]

Ren Fail
Zhang F, Yan L, Yang Y, Yu C, Peng Y, Wang Y.   +5 more
europepmc   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

Functional Predictors of Frailty and Kidney Disease Burden in Patients with End-stage Renal Disease Receiving Dialysis. [PDF]

J Frailty Sarcopenia Falls
Ward RR, Thompson ME, Trudelle-Jackson EE, Brizzolara KJ.   +3 more
europepmc   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source