Results 181 to 190 of about 488,885 (309)

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

WCN24-574 PLASMA EXCHANGE: EXPERIENCE FROM THE NEPHROLOGY DEPARTMENT AT SAHLOU CHU SOUSSE. TUNISIA

Kidney International Reports
Ndiaga Sow, Awatef Azzabi, Raja Boukadida, Wissal Sahtout, Sanda Mrabet, Rihem Dahmane, Mariam Sadaoui, Asma Fradi, Nesrine Thabet, Zeinabou Dede, Nerjes Ben Aicha, Achraf Jaziri, Maha Araoud, Yosra Guedri, Olfa Mahfoud, Dorsaf Zellama   +15 more
doaj   +1 more source

Development and validation of predictive models for the hemodialysis adequacy index (Kt/V) using multiple linear regression and machine learning algorithms. [PDF]

Front Digit Health
Li LL, Xu RF, Huang LL, Lu BR, Zhang ST, Tuo Y, Liu HQ, Ren R, Wang SF, Sun MX, Zhang XT, Zhao JR, Yu L, Meng Y.   +13 more
europepmc   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source

Development and Psychometric Evaluation of the Peritoneal Dialysis Treatment Adherence Scale: A Multicenter Methodological Study. [PDF]

Healthcare (Basel)
Aydın Z, Sarıbudak TP.
europepmc   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

Diffusion tensor MR neurography reveals altered sciatic and tibial nerve microstructure in chronic dialysis patients. [PDF]

Clin Kidney J
Fesselier M, Busecke J, Klein K, Raudonat C, Sam G, Weiler M, Khan-Blouki S, Jende JME, Heiland S, Zeier M, Bendszus M, Mooshage CM.   +11 more
europepmc   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Inpatient outcomes after primary total knee arthroplasty in patients receiving chronic dialysis: A nationwide propensity score-matched analysis. [PDF]

PLoS One
Nissan EC, Berkovich Y, Maman D, Steinfeld Y, Berkovich Y.   +4 more
europepmc   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source