Results 241 to 250 of about 488,885 (309)

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong   +13 more
wiley   +1 more source

Global Variation in Predictors of Uptake of Conservative Kidney Management: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Ren Care
Rosenberg KL   +7 more
europepmc   +1 more source

Overlap Between Mandatory and Voluntary Value-Based Kidney Care Model Participation and Home Dialysis Use.

open access: yesJAMA Health Forum
Tummalapalli SL   +5 more
europepmc   +1 more source

Dialysis

Seminars in Nephrology, 2001
Willem Kolff designed his "kunstmatige nier" in the early 1940s using spare parts obtained from the Wehrmacht; with it, he treated 14 patients with acute renal failure. Although there has been a tremendous improvement in the design and construction of dialysis machines, the basic concepts are unchanged.
Daelemans, R.A.   +2 more
openaire   +3 more sources

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