Results 81 to 90 of about 22,316 (265)

How reliable and robust are current biomarkers for copper status? [PDF]

, 2017
Cu is an essential nutrient for man, but can be toxic if intakes are too high. In sensitive populations, marginal over- or under-exposure can have detrimental effects.
Araya, Magdalena, Danzeisen, Ruth, Harrison, Brenda, Keen, Carl, McArdle, Harry J., Solioz, Marc, Thiele, Dennis   +6 more
core  

Microbial community dynamics and coexistence in a sulfide-driven phototrophic bloom [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Bhatnagar, S., Cowley, E. S., Kopf, S. H., Pérez Castro, S., Kearney, S., Dawson, S. C., Hanselmann, K.
Bhatnagar, Srijak, Castro, Sherlynette Pérez, Cowley, Elise S, Dawson, Scott C, Hanselmann, Kurt, Kearney, Sean, Kearney, Sean Michael, Kopf, Sebastian H, Pérez Castro, Sherlynette, Ruff, S. E   +9 more
core   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

Concomitant Prevalence of Low Serum Diamine Oxidase Activity and Carbohydrate Malabsorption

Canadian Journal of Gastroenterology and Hepatology, 2016
The aim of this retrospective study was to analyze the concomitant prevalence rates for lactose malabsorption (LM), fructose malabsorption (FM), and histamine intolerance (HI) in patients with so far unexplained gastrointestinal (GI) symptoms. A total of
Dietmar Enko, Andreas Meinitzer, Harald Mangge, Gernot Kriegshäuser, Gabriele Halwachs-Baumann, Eva Z. Reininghaus, Susanne A. Bengesser, Wolfgang J. Schnedl   +7 more
doaj   +1 more source

DFT‐Guided Design of a Multi‐Enzyme Mimetic High‐Entropy Nanozyme for Cascaded Glutathione Detection and Point‐of‐Care Testing

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Guided by density functional theory (DFT) calculations, a MnCoNiCuZnFe‐based Prussian blue analog (HEO) is screened out. It exhibits superior peroxidase (POD)‐like activity compared to noble metal‐incorporated high‐entropy nanozymes together with excellent oxidase (OXD) and glutathione oxidase (GSHOx)‐like activities.
Hua Lin, Li Ke, Shuran Wang, Ruoke Li, Shengmin Zhou, Yueling Liu, Huan Pang   +6 more
wiley   +1 more source

Regulation of lignan biosynthesis through signaling pathways mediated by H2O2 in Linum album cell culture in response to exogenous putrescine

Scientific Reports
Polyamines are small aliphatic amines whose metabolic reprogramming is involved in the regulation of various plant cellular reactions. Our previous study showed that polyamines increased lignan production in Linum album; however, little is known about ...
Elaheh Samari, Mohsen Sharifi, Farah Karimi, Reza H. Sajedi, Mostafa Sagharyan   +4 more
doaj   +1 more source

Exogenous Spermidine Promotes γ-Aminobutyric Acid Accumulation and Alleviates the Negative Effect of NaCl Stress in Germinating Soybean (Glycine max L.)

Foods, 2020
We investigated the effects of exogenous spermidine (Spd) on the physiological status, γ-aminobutyric acid (GABA) synthase activity, and gene expressions in germinating soybeans under NaCl stress.
Weiming Fang, Fei Qi, Yongqi Yin, Zhengfei Yang   +3 more
doaj   +1 more source

Dietary betaine supplementation improves growth performance, digestive function, intestinal integrity, immunity, and antioxidant capacity of yellow-feathered broilers

Italian Journal of Animal Science, 2021
To investigate the effects of dietary betaine supplementation on the growth performance, digestive function, intestinal integrity, immunity, and antioxidant capacity of yellow-feathered broilers, a total of 400 one-day-old female yellow-feathered ...
Yuduo Song, Rui Chen, Mi Yang, Qiang Liu, Yanmin Zhou, Su Zhuang   +5 more
doaj   +1 more source

Development of New Benzo[b]Thiophene‐2‐Carboxamide Derivatives as Advanced Glycation End‐Products Receptor (RAGE) Antagonists

ChemMedChem, Volume 21, Issue 1, January 2026.
A streamlined Ullmann‐Goldberg strategy enabled the synthesis of benzo[b]thiophene‐2‐carboxamides, promising ligands of the pro‐inflammatory RAGE receptor involved in inflammaging and age‐related diseases. LC‐MS, NMR, X‐ray and DFT studies elucidated the copper‐catalyzed mechanism. The lead compound, 3t’, shows inhibitory activity on the sRAGE/AGE2‐BSA
Lisa Bonin, Matthieu Hedouin, Christophe Furman, Ophélie Not, Steve Lancel, Mona Bensalah, Gael Coadou, Eric Boulanger, Sergiu Shova, Hassan Oulyadi, Alina Ghinet   +10 more
wiley   +1 more source

Depression Aggravates Immune‐Mediated Hepatitis Through NLRP3 Overactivation Induced by Intestinal Microbiota

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Depression is common in AIH patients and is associated with an elevated cirrhosis risk. AIH patients with depression, mice colonized with MDD microbiota, and ConA‐treated mice subjected to CUMS exhibit intestinal barrier dysfunction and hepatic NLRP3 inflammasome overactivation.
Simin Zhou, Liping Guo, Nian Chen, Haifeng Liu, Xin Liu, Jiwen Li, Shijing Dong, Jiangpeng Liu, Xiaoyi Wang, Ying Ran, Man Liu, Hongyu Chu, Yanni Li, Hui Yang, Jingwen Zhao, Lu Zhou   +15 more
wiley   +1 more source