Results 61 to 70 of about 10,147 (225)
Structure and Inhibition of Human Diamine Oxidase [PDF]
Biochemistry, 2009 Humans have three functioning genes that encode copper-containing amine oxidases. The product of the AOC1 gene is a so-called diamine oxidase (hDAO), named for its substrate preference for diamines, particularly histamine. hDAO has been cloned and expressed in insect cells and the structure of the native enzyme determined by X-ray crystallography to a ...
Aaron P, McGrath +7 more
openaire +2 more sources
Glia, Volume 74, Issue 9, September 2026.Mechanism of synthesis, release, receptor activation, uptake, and degradation of GABA in dorsal root ganglia (DRG). Left: GABA is synthesized from putrescine in satellite glial cells (SGCs). After being released by Best1 channel, it activates GABAA receptors in sensory neurons, producing a chloride current.
Natalie Jiménez‐Barrios +7 more
wiley +1 more source
Expression of diamine oxidase-like genes in mouse reproduction tracts [PDF]
, 2007 小鼠儲精囊液蛋白SVS I 與雙胺類氧化酶(DAO)在一級結構上具有56%的相似度，且兩者的基因Svs I與Abp1皆位於小鼠染色體相鄰的位置上。進一步基因組序列分析顯示小鼠染色體6B2.3區段內，Abp1-like genes具有分化叢集的現象。大鼠染色體4q23-4q24區段內的的Abp1-like genes也有相同的現象，但人類相對應的染色體7q36區段內僅有Abp1 的存在。演化樹的分析中顯示，Abp1-like genes是由共同的祖先所分化出來的。 小鼠的Abp1-like ...
Lin, Chun-Hui, 林純慧
core
Lactoferrin: similarity to diamine oxidase and purification by aminohexyl affinity chromatography [PDF]
, 1996 A protein reacting with a monoclal antibody against human placental diamine oxidase was purified from the specific granules of human neutrofil granulcytes using affinity chromatography on aminohexyl-divinylsulfonyl-agarose.
Nørskov, L. +3 more
core +1 more source
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Pioglitazone is an antidiabetic drug acting as a peroxisome proliferator‐activated receptor γ (PPARγ) agonist and later repositioned as a monoamine oxidase B (MAO‐B) inhibitor. Despite promising preclinical premises, it showed a lack of efficacy in clinical trials as a treatment for neurodegenerative diseases.
Filippo Basagni +12 more
wiley +1 more source
β-N-Methylamino-L-Alanine (BMAA) Modulates the Sympathetic Regulation and Homeostasis of Polyamines
Toxins, 2023 The neurotoxin β-N-methylamino-L-alanine (BMAA) is a non-proteinogenic amino acid produced by cyanobacteria. Non-neuronal toxicity of BMAA is poorly studied with a reported increase in reactive oxygen species and a decrease in the antioxidant capacity of
Milena Shkodrova +8 more
doaj +1 more source
Vancomycin Protects Against Lung Injury and Promotes Butyrate Metabolism
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Transplanting the fecal microbiota of patients with lung injury into mice causes an increase in LPS in the mice's blood, thereby leading to chronic lung injury in the mice. Meanwhile, oral administration of vancomycin can enhance colonic butyrate metabolism and improve lung injury in mice.
Jianuo Chen +9 more
wiley +1 more source
Diamine oxidase (DAO) in plasa and mucosa of weaned pigs. [PDF]
, 2014 abcMeans within a row with different letters differ significantly ...
Kan Xiao (623589) +4 more
core +1 more source
Ligand‐Level Chemical Activation: Coordination with Benefits
European Journal of Inorganic Chemistry, Volume 29, Issue 19, 2 July 2026.While often perceived as a liability, ligand‐based reactivity in carefully designed settings becomes a powerful synthetic tool. The key to streamlined processes overriding classical ionic reactivity is the selective electron redistribution induced by metal coordination. This enables storage of electrons and protons or incorporation of functional groups
Oscar Charpentier +2 more
wiley +1 more source
Diamine oxidase of Lathyrus sativus seedlings [PDF]
, 1976 A diamine oxidase has been purified (ca 40-fold) from 5-day old etiolated seedlings of L. sativus by MnCl2 treatment, (NH4)2SO4 and Me2CO fractionations, positive adsorption on alumina Cγ -gel followed by column chromatography on DEAE-Sephadex. This
Adiga, P. Radhakantha +2 more
core +1 more source