Results 1 to 10 of about 164,541 (160)

Polyamine Oxidase-Generated Reactive Oxygen Species in Plant Development and Adaptation: The Polyamine Oxidase—NADPH Oxidase Nexus [PDF]

Antioxidants, 2022
Metabolism and regulation of cellular polyamine levels are crucial for living cells to maintain their homeostasis and function. Polyamine oxidases (PAOs) terminally catabolize polyamines or catalyse the back-conversion reactions when spermine is ...
Péter Benkő, Attila Feher, Katalin Gémes   +2 more
exaly   +5 more sources

Exploring the Activity of Polyamine Analogues on Polyamine and Spermine Oxidase: Methoctramine, a Potent and Selective Inhibitor of Polyamine Oxidase [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1–9) or methoctramine (10–14) analogues, were evaluated as potential inhibitors or substrates of two enzymes of the polyamine catabolic pathway, spermine oxidase (SMOX) and ...
Manuela Cervelli, Maria Luisa Di Paolo, Enzo Agostinelli   +2 more
exaly   +4 more sources

Investigation of The Roles of Hydrogen Peroxide and NADPH Oxidase in The Regulation of Polyamine Metabolism in Maize Plants under Drought Stress Conditions [PDF]

Journal of Agricultural Sciences, 2022
The relationship between hydrogen peroxide and the metabolism of polyamines and the role of NADPH oxidase (NOX) in that relationship under drought conditions remains unclear.
Aykut Sağlam, Mehmet Demiralay, Fuat Yetişsin, Asım Kadıoğlu   +3 more
doaj   +2 more sources

Changes in Whole Blood Polyamine Levels and Their Background in Age-Related Diseases and Healthy Longevity

Biomedicines, 2023
The relationship between polyamines and healthy longevity has received much attention in recent years. However, conducting research without understanding the properties of polyamines can lead to unexpected pitfalls.
Kuniyasu Soda
doaj   +2 more sources

Improvment of cold tolerance of chickpea through heavy polyamines catabolism and ethylene phytohormone [PDF]

مجله بیوتکنولوژی کشاورزی, 2023
Objective The current study was undertaken to investigate if there is a relationship between metabolism of ethylene and heavy polyamines (PAs) under cold stress in cold-tolerant and cold-sensitive chickpea (Cicer arietinum L.) genotypes.
Saeed Amini, Reza Maali Amiri, Hasan Zeinali   +2 more
doaj   +1 more source

Amine oxidases as important agents of pathological processes of rhabdomyolysis in rats [PDF]

The Ukrainian Biochemical Journal, 2016
In this study we have tested an idea on the important role of amine oxidases (semicarbazide-sensitive amine oxidase, diamine oxidase, polyamine oxidase) as an additional source of oxidative/carbonyl stress under glycerol-induced rhabdomyolysis, since the
O. O. Gudkova, N. V. Latyshko, S. G. Shandrenko   +2 more
doaj   +1 more source

The Role of Spermidine and Its Key Metabolites in Important, Pathogenic Human Viruses and in Parasitic Infections Caused by Plasmodium falciparum and Trypanosoma brucei

Biomolecules, 2023
The triamine spermidine is a key metabolite of the polyamine pathway. It plays a crucial role in many infectious diseases caused by viral or parasitic infections.
Annette Kaiser
doaj   +1 more source

Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells

Frontiers in Pharmacology, 2020
Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation ...
Freddy López-Contreras, Freddy López-Contreras, Matías Muñoz-Uribe, Jorge Pérez-Laines, Laura Ascencio-Leal, Andrés Rivera-Dictter, Antonia Martin-Martin, Rafael A. Burgos, Pablo Alarcon, Rodrigo López-Muñoz   +9 more
doaj   +1 more source

Responses of Polyamine-Metabolic Genes to Polyamines and Plant Stress Hormones in Arabidopsis Seedlings

Cells, 2021
In plants, many of the enzymes in polyamine metabolism are encoded by multiple genes, whose expressions are differentially regulated under different physiological conditions.
Yusaku Yariuchi, Takashi Okamoto, Yoshiteru Noutoshi, Taku Takahashi   +3 more
doaj   +1 more source

Inhibiting Copper Amine Oxidase Using L-Aminoguanidine Induces Cultivar and Age-Dependent Alterations of Polyamine Catabolism in Tomato Seedlings

Agriculture, 2022
Many effects of polyamines (PAs) are well known in plant developmental processes; however, the significance of their catabolism is not well understood. Copper amine oxidase (CuAO) is involved in the degradation of diamine putrescine (Put).
Ágnes Szepesi, László Bakacsy, Henrietta Kovács, Árpád Szilágyi, Zoltán Márton Köhler   +4 more
doaj   +1 more source