Results 41 to 50 of about 18,577 (218)

Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis. [PDF]

, 2017
Helicobacter pylori is a gram-negative, microaerophilic bacterium that infects the stomach and can lead to, among other disorders, the development of gastric cancer. The inability of the host to clear the infection results in a chronic inflammatory state
Butcher, Lindsay D, Crowe, Sheila E, den Hartog, Gerco, Ernst, Peter B   +3 more
core   +2 more sources

Polyamine, peroxidase activity and total protein content during storage of bird-of-paradise [PDF]

, 2015
The present study was aimed to the determination of the effect of storage on some biochemical characteristics (PAs content, POX activity and total protein content) of flower tissue of bird-of-paradise.
de Moura, Fabiana Bezerra, de Souza, Angela Vacaro, Lima, Giuseppina Pace Pereira, Sim\uf5es, Adriano do Nascimento, Vianello, Fabio, Vieira, Marcos Ribeiro da Silva   +5 more
core  

Augmenter of liver regeneration [PDF]

, 2012
‘Augmenter of liver regeneration’ (ALR) (also known as hepatic stimulatory substance or hepatopoietin) was originally found to promote growth of hepatocytes in the regenerating or injured liver.
A Francavilla, A Francavilla, A Francavilla, A Francavilla, A Tury, AM Diehl, C Lu, C Thirunavukkarasu, C Thorpe, CG Morley, Chandrashekhar R Gandhi, CK Wu, CL Zanella, CR Gandhi, CR Gandhi, CR Gandhi, CS Sevier, D Becher, DJ Waxman, DL Coppock, DR LaBrecque, DR LaBrecque, E Assenat, E Gross, E Vitu, F He, FA McJunkin, G Hofhaus, G Hofhaus, G Stein, G Wang, GD Luk, GK Michalopoulos, GK Michalopoulos, GM Higgins, H Daub, H Iber, H Lange, H Lu, H Teir, I Higaki, J Gerber, J Lee, J Muntane-Relat, J Terblanche, JM Pascussi, JP Rose, K Blomquist, K Diekert, K Fujiwara, K Tanigawa, KJ Riehle, KL Hoober, KL Hoober, KL Hoober, L Polimeno, LS Field, M Hagiya, M Ilowski, M Ilowski, M Klissenbauer, M Levitchi, M Pinzani, M Terakura, M Tinel, M Zhang, ME Guicciardi, MT Donato, N Fausto, N Wiedemann, NL Vujanovic, P Honkakoski, R Dayoub, R Giorda, R Jover, R van Hoorn-Hickman, S Allen, S Nagoshi, SE Theocharis, SL Friedman, SR Farrell, T Lisowsky, T Lisowsky, T Lisowsky, T Lisowsky, T Lisowsky, T Lutz, TE Starzl, W Maret, W Maret, WE Fleig, WE Thasler, WE Thasler, Y Li, Y Li, Y Morel   +95 more
core   +2 more sources

Airborne 1O2 Delivery via a Superhydrophobic Dressing as a Pathway to Next‐Generation Wound Therapies, an in Vivo Murine Burn Model Study

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the SH bandage placed on an infected burn wound and its role in wound healing. A superhydrophobic PDMS membrane coated with the PS verteporfin is placed over the wound area and illuminated with a red laser at 690 nm, generating airborne 1O2 above the tissue.
Fernanda Viana Cabral, QianFeng Xu, Natalie Eidenschink, Pareesha Haresh, Alessandra Nara de Souza Rastelli, Jeremy Goverman, Alexander Greer, Alan M. Lyons, Tayyaba Hasan   +8 more
wiley   +1 more source

Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia

Journal of Neuroinflammation, 2020
Background Polyamine catabolism plays a key role in maintaining intracellular polyamine pools, yet its physiological significance is largely unexplored.
Kamyar Zahedi, Marybeth Brooks, Sharon Barone, Negah Rahmati, Tracy Murray Stewart, Matthew Dunworth, Christina Destefano-Shields, Nupur Dasgupta, Steve Davidson, Diana M. Lindquist, Christine E. Fuller, Roger D. Smith, John L. Cleveland, Robert A. Casero, Manoocher Soleimani   +14 more
doaj   +1 more source

Identification and Characterization of Novel Small-Molecule SMOX Inhibitors

Medical Sciences, 2022
The major intracellular polyamines spermine and spermidine are abundant and ubiquitous compounds that are essential for cellular growth and development. Spermine catabolism is mediated by spermine oxidase (SMOX), a highly inducible flavin-dependent amine
Amelia B. Furbish, Ahmed S. Alford, Pieter Burger, Yuri K. Peterson, Tracy Murray-Stewart, Robert A. Casero, Patrick M. Woster   +6 more
doaj   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

Advanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti, Valerio Di Lisio, Lucia Cardo, Alessandro Camilli, Estela Moretón Alfonsín, Daniele Cangialosi, Amaia Iturrospe Ibarra, Arantxa Arbe, Maurizio Prato   +8 more
wiley   +1 more source

Alterations of renal polyamine metabolism in mice with folic acid-induced chronic kidney disease

Biochemistry and Biophysics Reports
Chronic kidney disease (CKD) often follows acute kidney injury, leading to renal fibrosis and progressive renal failure. Spermine, a polyamine with antioxidant and anti-inflammatory properties, helps reduce renal fibrosis and may serve as a biomarker for
Cheng Xue, Jiaxin Chen, Xinming Li, Chenchen Zhou, Zhiguo Mao   +4 more
doaj   +1 more source

Discovery and antitumor evaluation of novel inhibitors of spermine oxidase

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Increasing knowledge of the relationship between cancer and dysregulated polyamine catabolism suggests interfering with aberrant polyamine metabolism for anticancer therapy that will have considerable clinical promise.
Lidan Sun, Jianlin Yang, Yu Qin, Yanlin Wang, Hongyan Wu, You Zhou, Chunyu Cao   +6 more
doaj   +1 more source

Cellular and Animal Model Studies on the Growth Inhibitory Effects of Polyamine Analogues on Breast Cancer

Medical Sciences, 2018
Polyamine levels are elevated in breast tumors compared to those of adjacent normal tissues. The female sex hormone, estrogen is implicated in the origin and progression of breast cancer.
T. J. Thomas, Thresia Thomas
doaj   +1 more source