Mathematical modelling of polyamine metabolism in bloodstream-form trypanosoma brucei: An application to drug target identification [PDF]
© 2013 Gu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Desmond J Higham +16 more
core +2 more sources
Semicarbazide diminishes the signs of bleomycin-induced pulmonary fibrosis in rats [PDF]
The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation.
O. O. Hudkova +5 more
doaj +1 more source
Modulation of polyamine catabolism in pea seedlings by calcium during salinity stress
The relation of polyamine catabolism in the response of Pisum sativum to salinity stress was investigated. Pea seedlings were grown in increasing concentrations of Na+ or K+ or at different concentration ratios of these ions. We studied the effect of Ca2+
Jana Piterková +4 more
doaj +1 more source
Study of the Characterization of Partial Purified Polyamine Oxidase from Sheep's Brain Tissue [PDF]
The study included partially purified of polyamine oxidase (PAO) from sheep's brain tissue by dialysis and ion exchange chromatography using DEAE-cellulose techniques. Tow isoenzymes (I،II) were obtained with specific activities 3.876 and 2.856 units/ mg
Wathba Ali, Sarah Younis
doaj +1 more source
Polyamine oxidase activity contributes to sustain maize leaf elongation under saline stress [PDF]
The possible involvement of apoplastic reactive oxygen species produced by the oxidation of free polyamines in the leaf growth of salinized maize has been studied here. Salt treatment increased the apoplastic spermine and spermidine levels, mainly in the
Menéndez, A.B. +3 more
core +2 more sources
Inhibition of Lymphocyte Proliferation by Polyamines Requires Ruminant-Plasma Polyamine Oxidase [PDF]
Spermine and spermidine in vitro are potent inhibitors of proliferation of phytohaemagglutinin-stimulated rat thymic lymphocytes, lymphoma cells and human lymphoblastic leukaemia cells, but only in media supplemented by foetal calf serum. This inhibition is shown to be due to a bovine plasma polyamine oxidase, with a high specificity for these ...
J C, Allen +4 more
openaire +2 more sources
The effect of exogenous γ-aminobutyric acid (GABA) and GABA synthesis inhibitor 3-mercaptopropionic acid (3-MP) on GABA metabolism and quality in fresh-cut pumpkin was investigated, and the possible mechanism was studied.
Jingyi LIANG +4 more
doaj +1 more source
Polyamine oxidase activity in blood of children infected with thalassemia in Nineveh governorate [PDF]
Polyamine Oxidase (PAO) )EC: 1.5.3.11( activity in serum of (20) cases of Untreated Thalaessamia, aged Six month to one year of both sexes, and (50) children of treated thalassmia, aged 1.5 to 15 years of Both sexes, and (50) normal children, aged six ...
Lana Mansour
doaj +1 more source
The polyamines spermidine, spermine and putrescine are essential for normal cellular functions. The contents of polyamines in tissue decreased in aged mice compared to young mice.
Takeshi Uemura +2 more
doaj +1 more source
Characterisation of the flavin adenine dinucleotide binding region in Myxococcus xanthus protoporphyrinogen oxidase [PDF]
This dissertation focuses on protoporphyrinogen oxidase (PPOX), the penultimate enzyme in the haem biosynthetic pathway. Partial defects in PPOX result in variegate porphyria, an autosomal dominant disorder.
Boateng, Mavis O
core +1 more source

