Results 21 to 30 of about 9,424 (130)

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Effect of Chitosan, Aloe vera Gel and Coconut Oil Edible Coatings on Postharvest Quality and Shelf Life of Strawberry (Fragaria × ananassa Duch) Under Ambient Storage

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Postharvest application of eco‐friendly edible coatings consisting of chitosan solution (CH), Aloe vera gel (AVG), and coconut oil (CO) on strawberry fruit under ambient conditions. Six distinct formulations (CH, AVG, CO, CH + AVG, CH + CO, and AVG + CO) along with a distilled water (control) were analyzed.
Gazi Mohammad Tasnimul Karim, Munmun Nahar, Soheli Sultana, Mrityunjoy Biswas   +3 more
wiley   +1 more source

Regulation of Quality and Phenolic Metabolism in Apricot Fruit by Postharvest Salicylic Acid and Putrescine Applications

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study evaluated the effects of salicylic acid and putrescine (1 mM) treatments on the quality and biochemical properties of apricot fruit during 30 days of cold storage. Although weight loss and decay increased during storage, applications significantly reduced these negative effects.
Mustafa Sakaldaş, Fatih Şen, Muttalip Gundogdu, Erdal Aglar   +3 more
wiley   +1 more source

Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza, Hyo In Kim, Paula Ketilly Nascimento Alves, Ailma Oliveira da Paixão, Ashlee Rasmussen, Sidharth Shankar, James Harbison, Vanessa Azevedo Voltarelli, Leo E. Otterbein   +8 more
wiley   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, Volume 5, Issue 2, Page 189-206, June 2026.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Bis(benzyl)polyamine analogs as novel substrates for polyamine oxidase.

Journal of Biological Chemistry, 1990
N,N'-Bis(benzyl)polyamine analogs were found to be substrates for highly purified polyamine oxidase. Metabolism of these analogs was apparently dependent on molecular O2 and resulted in the formation of benzaldehyde, H2O2, and a polyamine analog with free terminal amines.
A J, Bitonti, J A, Dumont, T L, Bush, D M, Stemerick, M L, Edwards, P P, McCann   +5 more
openaire   +2 more sources

Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's disease

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is characterized by the intracellular aggregation of the microtubule‐associated protein Tau. While the presence of large, insoluble neurofibrillary tangles has long been the primary focus of this research, a paradigm shift in the field now highlights smaller, soluble oligomers as the more neurotoxic Tau species leading
Joshua T. Skrehot, Dmitry Kurouski
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

GUS Reporter-Aided Promoter Deletion Analysis of A. thaliana POLYAMINE OXIDASE 3. [PDF]

Int J Mol Sci, 2023
Podia V, Chatzopoulos D, Milioni D, Stravopodis DJ, Dervisi I, Roussis A, Roubelakis-Angelakis KA, Haralampidis K.   +7 more
europepmc   +1 more source